Advertisement

Pneumotachographic Measurements of Lung Function in Preterm Infants with Respiratory Distress Syndrome

  • E. Kattner
  • K. Kosack
  • M. Obladen

Abstract

In newborn infants requiring artificial ventilation, the ventilator therapy usually is controlled and directed to obtain normal blood gases in the infant. Methods to ascertain lung function include the use of body plethysmography and measurement of esophageal pressure [2, 11, 25, 30], flow measurements by hot-wire anemometry [12], and pneumotachographic measurements [5, 11, 15, 22, 24, 26, 27]. Few data concerning compliance and resistance of the lung in small infants measured by pneumotachography are available. Due to variations in this technique there are often problems in comparing results. The aim of our study was to apply this objective method on term and preterm infants suffering from different lung problems particularly from respiratory distress syndrome and to gain data during the course of disease. Later this technique was also used to study lung mechanics in infants after surfactant replacement therapy.

Keywords

Lung Function Preterm Infant Tidal Volume Newborn Infant Lung Mechanic 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Avery ME, Cook CD (1961) Volume-pressure relationships of the lungs in fetal and adult goats. J Appl Physiol 16: 1034–1038PubMedGoogle Scholar
  2. 2.
    Beardsmore CS, Helms P, Stocks J, Hatch DJ, Silvermann M (1980) Improved esophageal balloon technique for use in infants. J Appl Physiol 49 (4): 735–742PubMedGoogle Scholar
  3. 3.
    Cook CD, Sutherland JM, Segal S, Cherry RB, Mead J, Mclllroy MB, Smith CA (1957) Studies of respiratory physiology in the newborn infant: III measurements of the mechanics of respiration. J Clin Invest 36: 440Google Scholar
  4. 4.
    Cook CD, Helliesen PJ, Agathon S (1958) Relation between mechanics of respiration, lung size and body size from birth to young adulthood. J Appl Physiol 13: 349–352PubMedGoogle Scholar
  5. 5.
    Cunningham MD, Desai NS (1986) Methods of assessment and findings regarding pulmonary function in infants less than 1000 grams. Clin Perinatol 13 (2): 229–313Google Scholar
  6. 6.
    Doershuk CF, Fisher BJ, Matthews LW (1975) Pulmonary physiology of the young child. In: Scarpelli EM (ed) Pulmonary physiology of the fetus, newborn and child. Lea and Febiger, PhiladelphiaGoogle Scholar
  7. 7.
    Gerhardt T, Bancalari E (1980) Chestwall compliance in full-term and premature infants. Acta Paediatr Scand 69: 359–364PubMedCrossRefGoogle Scholar
  8. 8.
    Giedion A, Haefliger A, Dangel P (1973) Acute pulmonary X-ray changes in hyaline membrane disease treated with artificial ventilation and positive endexpiratory pressure. Pediatr Radiol 1: 145PubMedCrossRefGoogle Scholar
  9. 9.
    Heaf DP, Turner H, Stock J, Helms P (1986) Lung compliance measurements in convalescent and sick intubated infants. In: Wolf P (ed) Neonatal physiological measurements. Butterworths, London, pp 249–255Google Scholar
  10. 10.
    Hjalmarson 0 (1974) Epidemiology and classification of acute neonatal respiratory disorders. Acta Paediatr Scand 70: 773–783CrossRefGoogle Scholar
  11. 11.
    Lachmann B (1981) Neonatal pulmonary mechanics during spontaneous ventilation. In: Scarpelli EM, Cosmi EV (eds) Reviews in perinatal medicine, vol 4. Raven, New York: 381–419Google Scholar
  12. 12.
    Lachmann B, Grossmann G, Freyse J, Robertson B (1981) Lung-thorax compliance in the artificially ventilated premature rabbit neonate in relation to variation in I:E ratio. Pediatr Res 15: 833–838PubMedGoogle Scholar
  13. 13.
    Leidig E, Noller F, Mentzel H (1986) Nichtinvasive kontinuierliche Überwachung der künstlichen Beatmung Früh-und Neugeborener durch fortlaufende Messung von Atemminutenvolumen, Sauerstoffaufnahme and Kohlendioxidabgabe. Klin Padiatr 198: 321–325PubMedCrossRefGoogle Scholar
  14. 14.
    Le Soeuf PN, Lopes JM, England SJ et al. (1983) Influence of chest wall distortion on esophageal pressure. J Appl Physiol 55: 353–364Google Scholar
  15. 15.
    Le Soeuf PN, England SJ, Bryan Ch (1984) Passive respiratory mechanics in newborns and children. Am Rev Respir Dis 129: 552–556Google Scholar
  16. 16.
    Mortola JP, Fisher JT, Smith B (1982) Dynamics of breathing in infants. J Appl Physiol 52: 1209PubMedGoogle Scholar
  17. 17.
    Nightingale DA, Richards CC (1964) Volume-pressure relations of the respiratory system of curarized infants. Anesthesiology 26 (6): 710–714CrossRefGoogle Scholar
  18. 18.
    Olinsky A, Bryan AC, Bryan MH (1976) A simple method of measuring total respiratory system compliance in newborn infants. S Afr Med J 50: 128–130PubMedGoogle Scholar
  19. 19.
    Polgar G (1961) Airway resistance in the newborn infant. J Pediatr 59 (6): 915–921PubMedCrossRefGoogle Scholar
  20. 20.
    Polgar J, Lacourt G (1972) A method for measuring respiratory mechanics in small newborn (premature) infants. J Appl Physiol 32 (4): 555–559PubMedGoogle Scholar
  21. 21.
    Richards CC, Bachmann L (1961) Lung and chestwall compliance of apneic paralysed infants. J Clin Invest 40: 273PubMedCrossRefGoogle Scholar
  22. 22.
    Rüttimann UE, Galioto FM jr, Franke JR, Rivera 0 (1981) Measurement of tracheal airflow in newborns by a differential flow system. Crit Care Med 9 (11): 801–804Google Scholar
  23. 23.
    Sandberg K, Dagbjartson A, Hjalmarson 0, Olsson T, Sjoquist BA (1982) Distribution of ventilation in healthy newborn infants and infants with transient tachypnea.Google Scholar
  24. 24.
    Simbruner G, Coradello H, Lubec G, Pollak A, Salzer H (1982) Respiratory compliance of newborns after birth and its prognostic value for the course and outcome of respiratory disease. Respiration 43: 414–423PubMedCrossRefGoogle Scholar
  25. 25.
    Stocks J, Levy NM, Godfrey S (1977) A new apparatus for the accurate measurement of airway-resistance in infancy. J Appl Physiol: 43 (1): 155–159PubMedGoogle Scholar
  26. 26.
    Swyer PR, Reiman RC, Wright JJ (1960) Ventilation and ventilatory mechanics in the newborn. J Pediatr 56: 612–622PubMedCrossRefGoogle Scholar
  27. 27.
    Thomson A, Silverman M (1985) Single-breath measurement of lung mechanics in VLBW-infants. Crit Care Med 13 (1): 4–8PubMedCrossRefGoogle Scholar
  28. 28.
    Thomson A, Silverman M. Single breath lung mechanics during mechanical ventilation of very low birthweight infants. In: Wolf P (ed) Neonatal physiological measurements. Butterworths, London, pp 268–274Google Scholar
  29. 29.
    Thomson A, Elliott J, Silverman M (1983) Pulmonary compliance in sick low birthweight infants. How reliable is the measurement of oesophageal pressure? Arch Dis Child 58: 891–896PubMedCrossRefGoogle Scholar
  30. 30.
    Warren RA, Alderson SH (1985) Calibration of computer-assisted (respicomp) respiratory inductive plethysmography in newborns. Am Rev Respir Dis 131: 564–567PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • E. Kattner
  • K. Kosack
  • M. Obladen

There are no affiliations available

Personalised recommendations