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Methods of Cell Immobilization

  • Chapter
Book cover Immobilization of Cells

Part of the book series: Biotechnology Monographs ((BIOTECHNOLOGY,volume 5))

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Abstract

Methods of cell immobilization roughly parallel those of enzyme immobilization and can best be classified by the nature of the mode of attachment, that is, as mechanical, chemical or ionic. In mechanical immobilization, the cells are localized by means of physical barriers. In chemical immobilization, covalent bonds are formed among cells or to a solid phase. In ionic immobilization, electrostatic, van der Waal’s or London forces of attraction are present. Cells can also attach themselves to solid supports in the course of natural growth, using a combination of these means. This classification is obviously not clear-cut but does serve the purpose of organizing the diverse methods of immobilization available. In Table 2.1, examples of cell immobilization are classified by mode of attachment.

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  1. Dept. of Chemical Engineering and Applied Chemistry, University of Toronto, Ontario, M5S 1A4, Canada

    Professor Dr. Colin R. Phillips & Dr. Yiu Cheong Poon

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Phillips, C.R., Poon, Y.C. (1988). Methods of Cell Immobilization. In: Immobilization of Cells. Biotechnology Monographs, vol 5. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73249-2_2

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