Zusammenfassung
Von verschiedenen Ländern und Rassen wurde der Anteil (Prozentsatz) der akralen Melanome an der Gesamtzahl der Melanome der Haut und die Inzidenz (jährlich neu auftretende Fälle akraler Melanome pro 100 000 Personen) des akralen Melanoms analysiert. Der Anteil des akralen Melanoms betrug 78,3 ± 11,4% für Schwarze, 58,3 ± 4,0% für Asiaten und 8,2 ± 1,2% für Weisse. Statistisch signifikante Unterschiede fanden sich zwischen Asiaten und Schwarzen (p < 0,02) und Asiaten und Weißen (p < 0,001). Die entsprechende Inzidenz betrug 0,47 ± 0,18, 0,23 ± 0,15 und 0,37 ± 0,22 (keine signifikanten Unterschiede). Damit ist das Auftreten des akralen Melanoms bei allen Rassen ungefähr gleich wahrscheinlich. Der hohe Anteil akralen Befalls bei Schwarzen und Asiaten kann durch die niedrige Rate der übrigen Melanome der Haut begründet werden, was vermutlich auf dem besseren Schutz der farbigen Haut mit ihrem effizienteren Melaninsystem gegen das Sonnenlicht beruht.
Summary
Acral melanoma proportion (percentage of acral melanoma of all skin melanomas) and acral melanoma incidence (annual number of new patients with acral melanoma per 100,000) of different countries and races were estimated. Acral melanoma proportion in Blacks, Asians, and Whites was 78.3 ± 11.4%, 58.3 ± 4.0%, and 8.2 ± 1.2% respectively (statistically significant differences: Black to Asians p < 0.02, Asians to Whites p < 0.001). Acral melanoma incidence was 0.47 ± 0.18, 0.23 ± 0.18 and 0.37 ± 0.22 respectively (statistically not significant). These findings suggest that acral melanoma arises at about the same rate in each race. The high proportion of acral melanoma in Blacks and Asians may be the results of relatively low occurrence of melanomas in other parts of skin, owing to their stronger melanin system to block the carcinogenic sunlight as compared with whites.
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Maie, O., Schnyder, U.W. (1987). Racial Differences in Acral Melanoma Incidence and Proportion (Critical Analysis from Literature). In: Hornstein, O.P., Hundeiker, M., Schönfeld, J. (eds) Neue Entwicklungen in der Dermatologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73248-5_4
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DOI: https://doi.org/10.1007/978-3-642-73248-5_4
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