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Acral-Ientiginöses Melanom

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Neue Entwicklungen in der Dermatologie

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Zusammenfassung

Der neu abgegrenzte acral-lentiginöse Melanomtyp kommt an Handtellern, Fußsohlen und subungual vor, ohne daß alle Melanome dieser Lokalisation acral-lentiginös sind. Entscheidend ist der histologische Befund. Die Ergebnisse der klinischen und histologischen Studien der letzten zehn Jahre werden dargestellt. Zur Zeit ist die Klassifikation des malignen Melanoms in die vier Typen erneut in Diskussion.

Summary

The newly recognized type of malignant melanoma, the acral lentiginous melanoma, occurs on the palmar, plantar and subungual skin. But the definition of the acral lentiginous melanoma is a histologic. Not all palmar and plantar melanomas are of acral lentiginous type. The results of the clinical and histological studies of the last ten years are given. The classification of malignant melanoma in the four types is in discussion at this time.

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Literatur

  1. Ackerman, A B: Malignant melanoma: A unifying concept. Hum. Path. 11, 591–595 (1980); Amer. J. Dermatopath. 2, 309–313 (1980).

    Article  CAS  PubMed  Google Scholar 

  2. Ackerman, A B: Disagreements about classification of malignant melanoma. Amer. J. Dermatopath. 4,447–452 (1982).

    Article  CAS  Google Scholar 

  3. Allen, A C, Spitz, S: Malignant melanoma. A clinico-pathological analysis of the criteria for diagnosis and prognosis, Cancer (Philad.) 6, 1–45 (1953).

    Article  CAS  Google Scholar 

  4. American Joint Committee for Cancer Staging and End-Results Reporting (AJC). Manual für Staging of Cancer. American Joint Comittee Chicago 1977.

    Google Scholar 

  5. Arrington, J H, Reed, R J, Ichinose, H, Krementz, E T: Plantar lentiginous melanoma: a distinctive variant of human cutaneous malignant melanoma. Amer. J. Surg. 1, 131–143 (1977).

    Article  Google Scholar 

  6. Baran, R, Haneke, E: Diagnostik und Therapie der streifenförmigen Nagelpigmentierung. Hautarzt 35, 359–365 (1984).

    CAS  PubMed  Google Scholar 

  7. Bondi, E E, Elder, D E, Guerry, I V, Clark jr, W H: Skin markings in malignant melanoma. JAMA (Chicago) 250, 503–505 (1983).

    CAS  Google Scholar 

  8. Booher, R J, Pack, G T: Malignant melanoma of the feet and hands. Surgery 4, 1084–1121 (1957).

    Google Scholar 

  9. Breslow, A: Tumor thickness, level invasion and node dissection in stage I cutaneous melanoma. Ann. Surg. 182, 572–575 (1975).

    Article  CAS  PubMed  Google Scholar 

  10. Clark jr, W H, From, L, Bernardino, E A, Mihm jr, E C: The histogenesis and biologic behavior of primary human malignant melanomas of the skin. Cancer Res. 29, 705–726 (1969).

    PubMed  Google Scholar 

  11. Clark jr, W H, Ainsworth, A M, Bernardino, E A, Yang, C H, Mihm jr, M C, Reed, R J: The developmental biology of primary human malignant melanomas: Seminars Oncol. 2, 83–103 (1975).

    Google Scholar 

  12. Clark jr, W H, Bernardino, E A, Reed, R J, Kopf, A W: Acral lentiginous melanomas including melanomas of mucous membranes. In: Clark jr, W H, Goldman, L I, Mastrangelo, M J: Human malignant melanoma, pp 109–124, New York, San Francisco, London: Grune & Stratton 1979.

    Google Scholar 

  13. Coleman, W P, Loria, P R, Reed, R J, Krementz, E T: Acral lentiginous melanoma. Arch. Derm. (Chicago) 116, 773–776 (1980).

    Google Scholar 

  14. Das Gupta, T K: Current concepts on malignant melanoma. Surg. Ann. 2, 183–206 (1976).

    Google Scholar 

  15. Davis, N: Cutaneous melanoma. The Queensland experience. Curr. Probl. Surg. 12, 5–63 (1976).

    Google Scholar 

  16. Duperrat, B: Le panaris mélanique. In: Actualités sur les tumeurs cutanées, pp 7–18, L’expansion scientifique Française, Paris 1963.

    Google Scholar 

  17. Elder, D E, Jucovy, P M, Clark jr, W H: Melanoma classification. A testable hypothesis. Amer. J. Dermatopath. 4, 443–445 (1982).

    Article  CAS  Google Scholar 

  18. Feibleman, C E, Stoll, H, Maize, J C: Melanomas of the palm, sole and nail-bed. Cancer (Philad.) 46, 2492–2504 (1980).

    Article  CAS  Google Scholar 

  19. Gibson, S H, Montgomery, H, Woolner, L B, Brunsting, L A: Melanotic whitlow (subungual melanoma). J. invest. Derm. 29, 119–129 (1957).

    CAS  PubMed  Google Scholar 

  20. Goldsmith, H S, Shaw, J K P, Kin, D H: Prognostic significance of lymph node dissection in the treatment of malignant melanoma. Cancer (Philad.) 26, 606–609 (1970).

    Article  CAS  Google Scholar 

  21. Haensch, R: Acral-lentiginöses Melanom (Palmar-plantar-Melanome). Abschlußsymposium d. AG „Malignes Melanom“ Freiburg/Br., 31.1.1981.

    Google Scholar 

  22. Haensch, R: Acral lentiginous melanoma (palmar/plantar melanoma). A retrospective study of 174 cases with clinical and prognostic features, pp 112, XYIth Int. Congr. of Dermatology, Tokyo 1982, Abstr. Series.

    Google Scholar 

  23. Haensch, R: Epidermale und mesenchymale Tumoren der Haut und malignes Melanom. In: Gross, R, Schmidt, C G: Klinische Onkologie 37.-37.61, Stuttgart, New York: Thieme-Verlag 1985.

    Google Scholar 

  24. Haneke, E, Baran, R: Subunguale Tumoren. Z. Hautkr. 57, 355–362 (1982).

    CAS  PubMed  Google Scholar 

  25. Haneke, E, Binder, D: Subunguales Melanom mit streifenförmiger Nagelpigmentierung. Hautarzt 29, 389–391 (1978).

    CAS  PubMed  Google Scholar 

  26. Heite, H-J: Ergebnisse der Arbeitsgemeinschaft „Malignes Melanom“ der DFG. Zbl. Hautu. Geschl.-Kr. 144, 2 (1980).

    Google Scholar 

  27. Hermanek, P: Histologie und Klassifikation. In: Weidner, F, Tonak, J: Das maligne Melanom der Haut, pp 63–73, Erlangen: Perimed-Fachbuch Verlags-GmbH 1981.

    Google Scholar 

  28. Hornstein, O P: Klinik und Diagnose. In: Weidner, F, Tonak, J: Das maligne Melanom der Haut, pp 27–49, Erlangen: Perimed-Fachbuch Verlags-GmbH 1981.

    Google Scholar 

  29. Hornstein, O P: Persönliche Mitteilung.

    Google Scholar 

  30. Hundeiker, M: Differentialdiagnose der Pigmentgeschwülste. Fortschr. Med. 97, 839–844 (1979).

    CAS  PubMed  Google Scholar 

  31. Hutchinson, J: Melanosis often not black: melanotic whitlow. Brit. med. J. 1, 493–495 (1886).

    Article  Google Scholar 

  32. Kerl, H, Hödl, S, Stettner, H: Acral lentiginous melanoma. In: Ackerman, A B (Ed): Pathology of malignant melanoma, pp 217–242, New York: Masson 1981.

    Google Scholar 

  33. Kerl, H: Das acral-lentiginöse Melanom: „Eine klinisch-morphologische Studie“. Zbl. Hautu. Geschl.-Kr. 144, 4 (1980).

    Google Scholar 

  34. Keyhani, A: Comparison of clinical behavior of melanoma of hands and feet. Cancer (Philad.) 40, 3168–3173 (1977).

    Article  CAS  Google Scholar 

  35. Kopf, A W: Subtile clues to diagnosis by gross pathology. Hutchinson’s sign of subungual malignant melanoma. Amer. J. Dermatopath. 3, 201–202 (1981).

    Article  CAS  Google Scholar 

  36. Kopf, WA, Bart, R S, Rodriguez-Sains, R S: Malignant melanoma: A review. J. derm. Surg. Oncol. 3,41–125 (1977).

    CAS  Google Scholar 

  37. Körting, G W, Bork, K: Carcinomserie. Das maligne Melanom. Ärztl. Mitt. 74, 2211–2216 (1977).

    Google Scholar 

  38. Krementz, E T, Reed, R J, Coleman III, W P, Sutherland, C M, Carter, R D, Campbell, M: Acral lentiginous melanoma. A clinicopathologic Entity. Ann. Surg. 195, 632–644 (1982)

    Article  CAS  PubMed  Google Scholar 

  39. Lederman, J S, Fitzpatrick, TB, Sober, A J: Skin markings in the diagnosis and prognosis of cutaneous melanoma. Arch. Derm. (Chicago) 120, 1449–1452 (1984).

    CAS  Google Scholar 

  40. Leppard, B, Sanderson, K V, Behan, F: Subungual malignant melanoma: Difficulty in diagnosis. Brit, med. J. 1, 310–312 (1974).

    Article  CAS  Google Scholar 

  41. Lieblich, L M: Classification of malignant melanoma. A view of the current controversy. Amer. J. Dermatopath. 4, 435–441 (1982).

    Article  CAS  Google Scholar 

  42. Lopansri, S, Mihm jr, M C: Clinical and pathological correlation of malignant melanoma. J. cutan. Path. 6, 180–194 (1979).

    Article  CAS  PubMed  Google Scholar 

  43. Lupulescu, A, Pinkus, H, Birmingham, D J, Unsdek, H K, Posch, IL: Lentigo maligna of the fingertip. Arch. Derm. (Chicago) 107, 717–722 (1973).

    CAS  Google Scholar 

  44. Maie, O, Schnyder, U W: Racial differences in acral melanoma incidence and proportion (critical analysis from literature). Zbl. Haut- u. Geschl.-Kr. 149, 969–973 (1985).

    Google Scholar 

  45. McGovern, V J: The nature of melanoma. A critical review. J. cutan. Path. 9, 61–81 (1982).

    Article  CAS  PubMed  Google Scholar 

  46. Mihm jr, M C, Clark’jr, W H, Reed, R J: The clinical diagnosis of malignant melanoma. Seminars Oncol. 2, 105–118 (1975).

    Google Scholar 

  47. Mihm jr, M C, Fitzpatrick, T B: Early detection of malignant melanoma. Cancer (Philad.) 37, 597–603 (1976).

    Article  Google Scholar 

  48. Miura, S, Jimbow, K: Clinical characteristics of subungual melanomas in Japan. Case report and a questionnaire survey of 108 cases. J. Derm. (Tokyo) 12, 393–402 (1985).

    CAS  Google Scholar 

  49. Nachbur, B; Die Perfusionsbehandlung des Extremitätenmelanoms. Bern, Stuttgart, Toronto: Verlag Hans Huber 1986.

    Google Scholar 

  50. Pack, G T, Adair, F E: Subungual melanoma. The differential diagnosis of tumors of the nail bed. Surgery 5, 47–72 (1939).

    Google Scholar 

  51. Pack, G T, Gerber, D M, Scharnagle, I M: End results in the treatment of malignant melanoma. A report of 1190 cases. Ann. Surg. 136, 905–911 (1952).

    Article  CAS  PubMed  Google Scholar 

  52. Pack, G T, Oropeza, R: Subungual melanoma. Surg. Gyn. Obstet. 124, 571–582 (1967).

    CAS  Google Scholar 

  53. Pannizon, R, Krebs, A: Das subunguale maligne Melanom. Hautarzt 31, 132–140 (1980).

    Google Scholar 

  54. Pannizon, R, Stieger, M, Schüler, G, Hardmeier, T: Das acral-lentiginöse Melanom: die jüngste Sonderform des malignen Melanoms der Haut. Schweiz, med. Wschr. 112, 612–618 (1982).

    Google Scholar 

  55. Patterson, R H, Helwig, E B: Subungual malignant melanoma: a clinicopathological study. Cancer (Philad.) 46, 2074–2987 (1980).

    Article  CAS  Google Scholar 

  56. Pehamberger, H: Das maligne Melanom der Haut. Prognose und Therapie. Wien, München, Bern: Verlag W. Maudrich 1984.

    Google Scholar 

  57. Petersen, N C, Bodenham, D C, Lloyd, O C: Malignant melanoma of the skin. Brit. J. plast. Surg. 15, 45–94 (1962).

    Google Scholar 

  58. Reed, R J: Acral lentiginous melanoma. In: Reed, R J: New concepts in surgical pathology of the skin, pp 89–90, New York: J. Wiley & Sons Inc. 1976.

    Google Scholar 

  59. Reed, R J, Ichinose, H, Clark jr, W H, Mihm jr, M C: Common and uncommon melanocytic nevi and borderline melanomas. Seminars Oncol. 2, 119–147 (1975).

    CAS  Google Scholar 

  60. Schmoeckel, C H, Braun-Falco, O: Prognostic index in malignant melanoma. Arch. Derm. (Chicago) 114,871–873 (1978).

    CAS  Google Scholar 

  61. Schmoeckel, C, Bockelbrink, A, Bockelbrink, J, Kontsis, J, Braun-Falco, O: Low- and high-risk malignant melanoma. I. Evaluation of clinical and histological prognosticators in 585 cases. Europ. J. Cancer 19, 227–235 (1983).

    Article  CAS  Google Scholar 

  62. Schmoeckel, C, Bockelbrink, A, Bockelbrink, H, Braun-Falco, O: Low- and high-risk malignant melanoma. II. Multivariate analysis for a prognostic classification. Europ. J. Cancer 19, 237–245 (1983).

    Article  CAS  Google Scholar 

  63. Schraffordt-Koops, H, Oldhoff, J, von der Ploeg, E, Vermey, A, Elbergen, R, Beekhuis, H: Some aspects of the treatment of primary malignant melanoma of extremities by isolated regional perfusion. Cancer (Philad.) 39, 27–35 (1977).

    Article  CAS  Google Scholar 

  64. Schraffordt-Koops, H, Oldhoff, J: Überleben und Lokalrezidiv nach regionaler hyperthermer Perfusion. In: Weidner, F, Tonak, J: Das maligne Melanom der Haut, pp 145–162, Erlangen: Perimed-Fachbuch Verlags-GmbH 1981.

    Google Scholar 

  65. Seebach, H B, Tille, M, Bahmer, F: Das maligne Melanom im Krebsregister des Saarlandes. 34. Tgg. DDG 20.-24. März 1985 Zürich, ref. Zbl. Haut- u. Geschl.-Kr. 150, 640 (1985).

    Google Scholar 

  66. Seiji, M, Mihm jr, M C, Sober, A J, Takahashi, M, Kato, T, Fitzpatrick, T B: Malignant melanoma of the palmar-plantar-subungual-mucosal type. Clinical and histopathological features. In: Pigment cell. Vol. 5, pp 95–104, Basel: Karger-Verlag 1979.

    Google Scholar 

  67. Seiji, M, Takahashi, M: Malignant melanoma with adjacent intraepidermal proliferation. Tohoku J. exp. Med. 114, 93–107 (1974).

    CAS  Google Scholar 

  68. Seiji, M, Takahashi, M: Plantar malignant melanoma. J. Derm. (Tokyo) 2, 163–170 (1975).

    CAS  Google Scholar 

  69. Sondergaard, K: The intraiesional variation of type, level of invasion, and tumour thickness of primary cutaneous malignant, melanoma. Acta path, scand., Sect. A, 88, 269–274 (1980).

    CAS  Google Scholar 

  70. Sondergaard, K, Olsen, G: Malignant melanoma of the foot. A clinicopathological study of 125 primary cutaneous malignant melanomas. Acta path, scand., Sect. A, 88, 275–283 (1980).

    CAS  Google Scholar 

  71. Suseelan, A V, Gupta, IM: Malignant melanoma in Nigeria - pathological studies. Afr. J. med. Sei. 6, 209–213 (1977).

    CAS  Google Scholar 

  72. Stehlin jr, J S, Giovanella, B C, De Ipolyi, P D, Muenz, L R, Anderson, R F: Results of hyperthermic perfusion for melanomas of the extremities. Surg. Gyn. Obstet. 140, 339–348 (1975).

    CAS  Google Scholar 

  73. Tonak, J, Weidner, F, Hofrichter, S, Altendorf A: Erlanger Therapieschema. Grundlagen, Ergebnisse und Behandlung von Rezidiven. In: Weidner, F, Tonak, J: Das maligne Melanom der Haut, pp 177–196, Erlangen: Perimed-Fachbuch Verlags-GmbH 1981.

    Google Scholar 

  74. Undeutsch, W, Ott, U: Das melanotische Panaritium (melanotic whitlow Hutchinson). Med. Welt 30, 54–58 (1979).

    CAS  PubMed  Google Scholar 

  75. Unio Internationalis Contra Cancrum (UICC): Melanom der Haut. In: TNM. Klassifikation der malignen Tumoren. 3. Aufl. Berlin, Heidelberg, New York: Springer 1979.

    Google Scholar 

  76. Unio Internationalis Contra Cancrum (UICC): TNM. Classification of malignant tumours. Ed. Harmer, M H, 3rd. ed., Geneva: UICC 1978.

    Google Scholar 

  77. Vazquez, M, Torres, S, Sanchez, J L: Malignant melanoma in Puerto Rico. Bol. Asoc. Med. PR 75, 8–10 (1983).

    Google Scholar 

  78. Väzquez, M, Ramos, F A, Sanchez, J L: Melanomas of volar and subungual skin in Puerto Rico. J. Amer. Acad. Derm. 10, 39–45 (1984).

    Article  Google Scholar 

  79. Wanebo, H J, Woodruff, J, Fortner, J G: Malignant melanoma of the extremities: a clinicopathological study using levels of invasion (microstage). Cancer (Philad.) 35, 666–676 (1975).

    Article  CAS  Google Scholar 

  80. Warner, T F C S, Hafez, G R, Padmalatha, C, Lange, T A: Acral lentiginous melanoma simulating “clear cell sarcoma of tendon and aponeuroses”. J. cutan. Path. 10, 193–200 (1983).

    Article  CAS  PubMed  Google Scholar 

  81. Weidner, F: Maligne Melanome der Haut. Früherkennung und Differentialdiagnose. Fortschr. Med. 98, 1317–1321 (1980).

    CAS  PubMed  Google Scholar 

  82. Wolff, W H: Gibt es unterschiedliche Melanomtypen? In: Wolff, H H, Schmeller, W: Fehlbildungen, Naevi, Melanome, pp 194–197, Berlin, Heidelberg, New York, Tokyo: Springer 1985.

    Google Scholar 

Addendum

  1. Arundell, FD: Screening for melanoma and skin cancer. JAMA (Chicago) 255, 2443–2444 (1986)

    CAS  Google Scholar 

  2. Arundell, F D: Campaigns for the detection and prevention of melanoma and skin cancers. J. Amer. Acad. Derm. 16, 406–407 (1987)

    Article  Google Scholar 

  3. Bork, K: Sub- und periunguale Pigmentflecken. Therapiewoche 35, 854–855 (1985)

    Google Scholar 

  4. Braun-Falco, O, Landthaier, M, Holzel, D, Konz, B, Schmoeckel, C: Therapie und Prognose maligner Melanome der Haut. Dtsch. med. Wschr. 111, 1750–1756 (1986)

    CAS  Google Scholar 

  5. Cascinelli, N, Ferrario, M, Tonelli, T, Leo, E: A possible new tool for clinical diagnosis of melanoma: the computer. J. Amer. Acad. Derm. 16, 361–367 (1987)

    Article  CAS  Google Scholar 

  6. Cassileth, B R, Clark, W J jr, Lusk, E J, Frederick, B E, Thompson, C J, Walsh, W P: How well do physicians recognize melanoma and other problem lesions? J. Amer. Acad. Derm. 14, 555–560 (1986)

    Article  CAS  Google Scholar 

  7. Fletcher, J R, White, C R, Fletcher, W S: Improved survival rates of patients with acral lentiginous melanoma treated with hyperthermic isolation perfusion, wide excision, and regional lymphadenectomy. Amer. J. Surg. 151, 593–598 (1986)

    Article  CAS  PubMed  Google Scholar 

  8. Freidman, R J, Rigel, D S, Kopf, A W: Early detection of malignant melanoma: the role of physician examination and self-examination of the skin. CA 35, 130–151 (1985)

    Google Scholar 

  9. Goth, D: Zur Problematik des malignen Melanom. Handchirurgie 16, Suppl., 60–62 (1984)

    Google Scholar 

  10. Haneke, E: Pathogenese der Nageldystrophie beim subungualen Melanom. Verh. dtsch. Ges. Path. 70, 484 (1986)

    Google Scholar 

  11. Hundeiker, M: Differentialdiagnose der malignen Melanome. Woran muß bei pigmentierten Hauttumoren noch-gedacht werden? Therapiewoche 35, 846–853 (1985)

    Google Scholar 

  12. Hundeiker, M: Frühdiagnose bei malignen Melanomen. Symposion in der Fachklinik Hornheide, Münster, 8. Nov. 1986. Ref. Zbl. Haut- u. Geschl.-Kr. 152, 732–733 (1986)

    Google Scholar 

  13. Klemm-Mayer, H: Akral-lentiginöses Melanom des rechten Zeigefingers. Z. Hautkr. 60, 681 (1985)

    Google Scholar 

  14. Mackie, R M: Malignant melanocytic tumours. J. cutan. Path. 12, 251–265 (1985)

    Article  CAS  PubMed  Google Scholar 

  15. McGovern, V J, Cochran, A J, Esch, E P van der, Little, J H, MacLennan, R: The classification of malignant melanoma, its histological reporting and registration: a revision of the 1972 Sydney classification. Pathology 18, 12–21 (1986)

    Article  CAS  PubMed  Google Scholar 

  16. Michel, U, Hornstein, O P, Schönberger, A: Infrarotthermographie bei malignem Melanom. Möglichkeiten und Grenzen. Hautarzt 36, 83–89 (1985)

    CAS  PubMed  Google Scholar 

  17. Milburn, P B, Silvers, D N, Sian, C S: The color of the skin of the palm and soles as a possible clue to the pathogenesis of acral-lentiginous melanoma. Amer. J. Dermatopath. 4, 429–433 (1982)

    Article  CAS  Google Scholar 

  18. Paladugu, R R, Winberg, C D, Yonemoto, R H: Acral lentiginous melanoma. A clinicopathologic study of 36 patients. Cancer (Philad.) 52, 161–168 (1983)

    Article  CAS  Google Scholar 

  19. Raderman, D, Giler, S, Rothem, A, Ben-Bassat, M: Late metastases (beyond ten years) of cutaneous malignant melanoma. J. Amer. Acad. Derm. 15, 374–378 (1986)

    Article  CAS  Google Scholar 

  20. Schmoeckel, C, Wagner-Grösser, G, Braun-Falco, O: Klinische Diagnostik initialer maligner Melanoma. Hautarzt 36, 558–562 (1985)

    CAS  PubMed  Google Scholar 

  21. Schulz, H: Problematik der Makrodiagnostik maligner Melanome und ihrer Frühformen. Symposion in der Fachklinik Hornheide, Münster, 8. Nov. 1986. Ref. Zbl. Haut- u. Geschl.-Kr. 152, 733 (1986)

    Google Scholar 

  22. Seebach, H B, Tille, M M, Bahmer, F: Das maligne Melanom der Haut im Krebsregister des Saarlandes 1968–1981. Pathologe 6, 231–241 (1985)

    Google Scholar 

  23. Steen, M, Bugyi, S, Zellner, P-R, Wegener, K: Malignes Melanom des Nagelbettes unter einem Hauttransplantat. Handchirurgie 18, 209–213 (1986)

    CAS  Google Scholar 

  24. Takematsu, H, Obata, M, Tomita, Y, Kato, T, Täkahashi, M, Abe, R: Subungual melanoma. A clinicopathologic study of 16 Japanese cases. Cancer (Philad.) 55, 2725–2731 (1985)

    Article  CAS  Google Scholar 

  25. Tallone, P, Berrino, P, Fdrris, A, Santi, P L: Lentigo maligna amelanica acralis. Chron. Derm. 16, 855–859 (1985)

    Google Scholar 

  26. Weidner, F: Die Formenvielfalt maligner Melanome. Therapiewoche 35, 840–844 (1985)

    Google Scholar 

  27. Wolff, K, Pehamberger, H: Malignes Melanom: Früherkennung und Prognose. Wien. klin. Wschr. 97, 451–455 (1985)

    CAS  Google Scholar 

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  1. Universitätshautklinik Düsseldorf, Moorenstr. 5, 4000, Düsseldorf, Deutschland

    R. Haensch

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  1. Erlangen, Deutschland

    O. P. Hornstein

  2. Münster-Hornheide, Deutschland

    M. Hundeiker

  3. Mannheim, Deutschland

    J. Schönfeld

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Haensch, R. (1987). Acral-Ientiginöses Melanom. In: Hornstein, O.P., Hundeiker, M., Schönfeld, J. (eds) Neue Entwicklungen in der Dermatologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73248-5_3

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  • DOI: https://doi.org/10.1007/978-3-642-73248-5_3

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