Total Androgen Blockade

  • Fritz H. Schröder
Conference paper
Part of the ESO Monographs book series (ESO MONOGRAPHS)

Abstract

In most Western countries prostatic cancer is the second to third most frequent cause of cancer death in males. The death rate from this tumor has not changed throughout the years. This is mainly due to the fact that most prostatic carcinomas are diagnosed in a metastatic stage. Unfortunately, an effective, curative treatment of this disease is not known [1]. Endocrine management, which produces excellent palliation in 70-80% of all cases, which is associated with an objective response in 20-40% and a significant prolongation of the symptom-free interval, never, or almost never, leads to the cure of a patient. Due to the high incidence of competing causes of death, many patients die with, rather than of, their prostatic carcinoma. Some response rates obtained in recent prospective randomized trials are summarized in Table 1.

Keywords

Estrogen Adenocarcinoma Testosterone Androgen Alan 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • Fritz H. Schröder
    • 1
  1. 1.Department of UrologyErasmus UniversityRotterdamThe Netherlands

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