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Production and Measurement of Interleukin 2 and Interleukin 3

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Book cover The Pharmacology of Lymphocytes

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 85))

Abstract

In 1979, at the Second International Lymphokine Workshop, it was decided to revise the nomenclature for antigen-nonspecific T cell proliferation and helper factors (Aarden et al. 1979). The term “interleukin” was created as a common denominator for lymphokines acting among different leukocytes. Since then, the field of lymphokine research has made great progress. This is in part due to the many new technical developments which have been applied to lymphokine research, such as improved tissue culture techniques (Chap. 12), the availability of monoclonal antibodies (Chap. 6), and better biochemical separation techniques followed by the possibility of microsequencing. The greatest impact on lymphokine research was the use of recombinant DNA technology which allowed a molecular understanding of many lymphokines.

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  1. B. M. Stadler
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  2. K. Hirai
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  3. J.-F. Gauchat
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  1. Research Department, CIBA-GEIGY AG, CH-4002, Basel, Switzerland

    Michael A. Bray Ph. D.

  2. Pharmaceutical Division, Preclinical Research, SANDOZ Ltd., CH-4002, Basel, Switzerland

    John Morley Ph. D., FRC Path.

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© 1988 Springer-Verlag Berlin Heidelberg

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Stadler, B.M., Hirai, K., Gauchat, JF. (1988). Production and Measurement of Interleukin 2 and Interleukin 3. In: Bray, M.A., Morley, J. (eds) The Pharmacology of Lymphocytes. Handbook of Experimental Pharmacology, vol 85. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73217-1_9

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