Abstract
The term “lymphocyte activation” has been used interchangeably with lymphocyte transformation, blastogenesis, and mitogenesis. Occasionally, the term indicates only early T lymphocyte events such as volume changes or lymphokine production, but usually it refers to induction of proliferation. In this chapter lymphocyte activation will be used to denote the process that begins with the binding of mitogenic agents or antigens to lymphocyte surface receptors, stimulating the cells to leave the quiescent G0 stage and traverse the G1 and S phases.
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Coffey, R.G. (1988). Intracellular Events During Lymphocyte Activation. In: Bray, M.A., Morley, J. (eds) The Pharmacology of Lymphocytes. Handbook of Experimental Pharmacology, vol 85. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73217-1_5
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