Splenic Tumors

  • J. N. Bruneton
  • C. Balu-Maestro
  • J. Drouillard
  • F. Normand
  • J. G. Fuzibet


Tumors of the spleen are uncommon and often asymptomatic. Most malignant splenic tumors have a lymphomatous etiology. The main risk with benign lesions is hemorrhage. Although the sonographic features of splenic tumors are usually nonspecific, the sensitivity of the technique appears satisfactory, except for lymphomas. Ultrasound detection of focal nonlymphomatous lesions warrants further investigation by computed tomography for accurate diagnosis.


Cavernous Hemangioma Sonographic Feature Splenic Cyst Splenic Lesion Splenic Metastasis 
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  1. Anjou A, Chollat L, Bret PM, Bretagnolle M, Valette PJ, Poix D (1983) Apport de la tomodensitométrie dans la pathologie splénique focalisée. Ann Radiol 26: 275–283PubMedGoogle Scholar
  2. Arnold J, Mac Gahan JP, Stadalnick RC (1982) Epidermoid cyst of the spleen: value of non-invasive imaging modalities in preoperative diagnosis. J Comput Assist Tomogr 6: 836–838PubMedCrossRefGoogle Scholar
  3. Balu C, Bruneton JN, Fenart D, Nicolau A, Roux P, Caramella E (1984) Examen clinique et échographique. Valeur comparée dans l’exploration des masses de l’hypochondre gauche. Concours Médical 106: 2081–2086Google Scholar
  4. Balu-Maestro C, Bruneton JN, Denis F, Fenart D, Abbes M, Normand F (1986) Hémangiome caverneux de la rate. J Radiol 67: 247–250PubMedGoogle Scholar
  5. Bevilacqua G, Toni G, Tuoni M (1976) A case of cavernous hemangioma of the spleen. Tumori 62: 485–492PubMedGoogle Scholar
  6. Bisker J, Mac Carthy J (1983) Computed tomographic demonstration of colonic carcinoma metastatic to the spleen. Comput Radiol 7: 193–194PubMedCrossRefGoogle Scholar
  7. Bostick WL (1945) Primary splenic neoplasms. Am J Path 21: 1143PubMedGoogle Scholar
  8. Brinkley AA, Lee JR (1981) Cystic hamartoma of the spleen. CT and sonographic finding. J Clin Ultrasound 9: 136–138PubMedCrossRefGoogle Scholar
  9. Bruneton JN, Philippe JC, Balu C, Drouillard J, Caramella E, Roux P (1983) L’échographie en pathologie tumorale de la rate: limites et perspectives. Rev Fr Hématol 25: 355–361Google Scholar
  10. Bruneton JN, Matter D, Benozio M, Senecail B (1984) Echographie en pathologie tumorale de l’adulte. Masson, ParisGoogle Scholar
  11. Bruneton JN, Manzino JJ, Caramella E (1986) Gastrointestinal lymphomas. In: Bruneton JN, Schneider M (eds) Radiology of lymphomas. Springer, Berlin Heidelberg New York Tokyo, pp 70–89CrossRefGoogle Scholar
  12. Buff SJ, Forster WL (1980) Left upper quadrant mass. Invest Radiol 15: 465–468PubMedCrossRefGoogle Scholar
  13. Carpenter G, Cotter PW, Davidson JRM (1986) Epidermoid cyst of the spleen. Aust NZ J Surg 56: 365–368CrossRefGoogle Scholar
  14. Combe J, Lorthioir JM, Muenier CL, Pageaut G, Dreyfus A, Millon G, Milleret P (1980) Lymphangiome kystique de la rate. J Chir 117: 547–550Google Scholar
  15. Dawes LG, Malangoni MA (1986) Cystic masses of the spleen. Am Surg 52: 333–336PubMedGoogle Scholar
  16. De Graaff CS, Taylor KJW, Jacobson Z (1979) Grey scale echography of the spleen. Follow-up in 67 patients. Ultrasound Med Biol 5: 13–21PubMedCrossRefGoogle Scholar
  17. Ellison RB (1980) Radiologic Seminar CCI: Cystic lymphangioma. A consideration in asymptomatic massive cystic splenomegaly. J Miss State Med Assoc 21: 67–68PubMedGoogle Scholar
  18. Federle M, Moss AA (1983) Computed tomography of the spleen. CRC Crit Rev Diag Imaging 19: 1–16Google Scholar
  19. Garcia Correa F, Febles Molina G, Perez Frias P, Alonso Gonzalez MA (1985) Quieste seroso del bazo. Rev Esp Enf Ap Digest 68: 162–165Google Scholar
  20. Glees JP, Taylor KJW, Gazet JC, Peckham MJ, Mc Cready VR (1977) Accuracy of grey-scale ultrasonography of liver and spleen in Hodgkin’s disease and the other lymphomas compared with isotope scans. Clin Radiol 28: 233–238PubMedCrossRefGoogle Scholar
  21. Goldfinger M, Cohen MM, Steinhardt MI, Roth-berg R, Rother I (1986) Sonography and percutaneous aspiration of splenic epidermoid cyst. J Clin Ultrasound 14: 147–149PubMedCrossRefGoogle Scholar
  22. Husni EA (1961) The clinical course of splenic hemangioma. Arch Surg 83: 681–688PubMedCrossRefGoogle Scholar
  23. Issa M, Buemi A, Holderbach LJ, Ratignier A, Laedlein-Greilsamer D, Sengler J (1984) Kyste enteroïde de la rate: une nouvelle entité? J Chir 121: 425–429Google Scholar
  24. Kishikawa T, Nymaguchi Y, Watanabe K, Matsuura K (1978) Angiographic diagnosis of benign and malignant splenic tumors. AJR 130: 339–344PubMedGoogle Scholar
  25. Labbe A, Vanneuville G, Goomy P, Tanguy A, Vial-let JF (1981) Kyste épidermoïde de la rate chez l’enfant. A propos d’une observation. Ann Radiol 24: 525–529PubMedGoogle Scholar
  26. Leonard JC, Barnes PD, Kern JD (1981) Splenic hemangioma. Clin Nucl Med 6: 89PubMedCrossRefGoogle Scholar
  27. Lorenz R, Beyer D, Friedmann G, Mödder U (1983) Grenzen der Differenzierung fokaler Milzläsionen durch Sonographie und Computertomographie. RÖFO 138: 447–452PubMedGoogle Scholar
  28. Manor A, Starinsky R, Garfinkel D, Yona E, Modai D (1984) Ultrasound features of a symptomatic splenic hemangioma. J Clin Ultrasound 12: 95–97PubMedCrossRefGoogle Scholar
  29. Meyer JE, Harris NL, Elman A, Stomper PC (1983) Large cell lymphoma of the spleen: CT appearance. Radiology 148: 199–201PubMedGoogle Scholar
  30. Mittelstaedt CA, Partain CL (1980) Ultrasonic-pathologic classification of splenic abnormalities: gray scale patterns. Radiology 134: 697–705PubMedGoogle Scholar
  31. Murphy JF, Bernardino ME (1979) The sonographic findings of splenic metastases. J Clin Ultrasound 7: 195–197PubMedCrossRefGoogle Scholar
  32. Nahman B, Cunningham JJ (1985) Sonography of splenic angiosarcoma. J Clin Ultrasound 13: 354–356PubMedCrossRefGoogle Scholar
  33. Newmark H (1982) Breast cancer metastasizing to the spleen seen on computerized tomography. Comput Radiol 6: 53–55PubMedCrossRefGoogle Scholar
  34. Noya G, Riberti C, Dettori G, Bacciu PP, Sala A, Gauisai D, Urigo F, Bigglioli P (1984) L’emangioma cavernose splenico. Minerva Med 75: 483–486PubMedGoogle Scholar
  35. Ohta M, Tsutsumi Y, Tanaka Y (1986) Splenic hamartoma. Acta Pathol Jpn 36: 471–480PubMedGoogle Scholar
  36. Pakter RL, Fishman EK, Nussbaum A, Giargiana FA, Zerhouni EA (1987) CT findings in splenic hemangiomas in the Klippel-Trenaunay-WeberSyndrome. J Comput Assist Tomogr 11: 88–91PubMedCrossRefGoogle Scholar
  37. Piekarski J, Federle MP, Moss AA, London SS (1980) Computed tomography of the spleen. Radiology 135: 683–689PubMedGoogle Scholar
  38. Pyatt RS, Williams ED, Clark M, Gaskins R (1981) CT diagnosis of splenic cyst lymphangiomatosis. J Comput Assist Tomogr 5: 446–448PubMedCrossRefGoogle Scholar
  39. Quilichini MA, Clot P, Viandier A, Gayet B, Douard MC, Vaquino G (1983) Kyste épidermoïde de la rate. A propos de 2 cas. Ann Chir 37: 341–344PubMedGoogle Scholar
  40. Rappaport H (1966) Tumors of the hematopoietic system. Atlas of tumor pathology, Sect III, Fasc 8. AFIP, Washington, pp 91–204Google Scholar
  41. Rosenthall T, Adar R, Wolfstein I, Deutsch V (1973) Cavernous hemangioma of the spleen; angiographic observations. Angiology 24: 430–433CrossRefGoogle Scholar
  42. Sandermann J (1981) Secondary calcified splenic cyst. Acta Chir Scand 147: 725–727PubMedGoogle Scholar
  43. Segal I, Fancourt MN, Kecker GAG, Hodgkin-son JH (1977) Cavernous hemangioma of the spleen. A case report. J South Mr Med Assoc 51: 637–638Google Scholar
  44. Sekiya T, Meller ST, Cosgrove O, Mac Ready VR (1982) Ultrasonography of Hodgkin’s disease in the liver and spleen. Clin Radiol 33: 635–639PubMedCrossRefGoogle Scholar
  45. Siler J, Hunter TB, Weiss J, Haber K (1980) Increased echogenicity of the spleen in benign and malignant disease. AJR 134: 1011–1014PubMedGoogle Scholar
  46. Solbiati L, Bossi MC, Bellotto E, Ravetto C, Montali G (1983) Focal lesions in the spleen. Sono-graphic patterns and guided biopsy. AJR 140: 59–65PubMedGoogle Scholar
  47. Spalding RM, Jennings CU, Yam LT (1980) Splenic hamartoma. Br J Radiol 53: 1197–1200PubMedCrossRefGoogle Scholar
  48. Thomas JL, Bernardino ME, Vermess M, Bernes PA, Fuller LM, Hagemeister FB, Doppman J, Fisher RI, Longo DL (1982) EOE-13 in the detection of hepatosplenic lymphoma. Radiology 145: 629–634PubMedGoogle Scholar
  49. Tran-Minh V, Pichat L, Giuy J, Valla JS, Mollard P (1980) Kyste épidermoïde de la rate. Signe écho-graphique inhabituel. Ann Radiol 23: 429–430PubMedGoogle Scholar
  50. Vermess M, Bernardino ME, Doppmann JL, Fisher RI, Thomas JL, Velasquez WS, Fuller LM, Russo A (1981) Use of intravenous liposoluble contrast material for the examination of the liver and spleen in lymphoma. J Comput Assist Tomogr 5: 700–713Google Scholar
  51. Vermess M, Doppmann JL, Sugarbaker PH, Fisher RI, O’Leary TS, Chatterji DC, Grimes G, Adamson RH, Willis M, Edwards BK (1982) Computed tomography of the liver and spleen with intravenous lipoid contrast material: review of 60 examinations. AIR 138: 1063–1071Google Scholar
  52. Zornoza J, Ginaldi S (1981) Computed tomography in hepatic lymphoma. Radiology 138: 405–410PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • J. N. Bruneton
  • C. Balu-Maestro
  • J. Drouillard
  • F. Normand
  • J. G. Fuzibet

There are no affiliations available

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