Vacuole Division and Inheritance in Saccharomyces Cerevisiae

  • Brenda Guthrie
  • William Wickner
Conference paper
Part of the NATO ASI Series book series (volume 16)


Cell division requires the partitioning of cytoplasmic components to ensure daughter cell viability. Some organelles, such as ribosomes, may partition at cytokinesis simply by their abundant distribution throughout the cytoplasm (Birky,1983). Other organelles that are present singly or in low copy number must divide and segregate in a more regulated fashion (Warren,1985). In higher eukaryotic cells, the Golgi apparatus, endoplasmic reticulum, and nuclear membrane fragment at the start of mitosis (Burke et al.,1982, Lipski and Pagano, 1985, Zeligs and Wollman, 1979, Gerace and Blobel, 1980). This fragmentation event may enable the partitioning of organelle components into the daughter cell.


Daughter Cell Methyl Benzimidazole High Eukaryotic Cell Cell Cycle Position Common Cytoplasm 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • Brenda Guthrie
    • 1
  • William Wickner
    • 1
  1. 1.Department of Biological Chemistry and the Molecular Biology InstituteUniversity of CaliforniaLos AngelesUSA

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