Serine Metabolism, beta-Carbolines and Psychoses

  • J. Bruinvels
  • L. Pepplinkhuizen
  • D. Fekkes
Conference paper
Part of the NATO ASI Series book series (volume 20)


The striking potency of substances from exogenous sources — like hashish, mescaline or LSD — to evoke mental states similar to certain phenomena observed in psychotics, made many researchers speculate about the origin of psychoses. In this respect most at­tention was focussed on altered sensory perception of surroundings, distances, time, body, colours etc. and on subjective experiences of feelings of oneness and understand­ing of the universe. These so-called psychedelic experiences (1) have been noted in a variety of psychotic disorders including schizophrenia.


Serine Hydroxymethyltransferase Chronic Schizophrenic Patient Tetrahydrofolic Acid Chotic Symptom Schizoaffective Psychosis 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • J. Bruinvels
    • 1
  • L. Pepplinkhuizen
    • 1
  • D. Fekkes
    • 1
  1. 1.Biological Psychiatry Group Departments of Pharmacology and PsychiatryErasmus University RotterdamRotterdamThe Netherlands

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