The Mechanism of Acetylcholine Release: Its Essential Component, the Mediatophore
In a dialogue on virtue the greek philosopher Platon opposes his master Socrate to Menon. Socrate could paralyse his contradictors with a ferocious critique, this leads Menon to compare him to the sea water fish the Torpedo which numbs its preys. Socrate followed the joke but points out that like the paralysed prey the Torpedo is itself numbed after the attack.(ref. 14). Such an essential aspect of the Torpedo physiology (the fatigue after the discharge) had therefore been observed some 400 years B.C.
KeywordsRelease Mechanism Transmitter Release Acetylcholine Release Artificial Membrane Presynaptic Membrane
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