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A Biological Approach to Assessing Environmental Risks of Engineered Microorganisms

  • Lawrence W. Barnthouse
  • Gary S. Sayler
  • Glenn W. SuterII
Conference paper
Part of the NATO ASI Series book series (volume 18)

Abstract

Many environmental applications of biotechnology involve deliberate release of organisms into the environment, where they must survive and multiply to perform their functions. Examples of such applications include degradation of toxic chemicals and in-situ leaching of ores. It is natural, when developing a scheme for assessing environmental risks of these microorganisms, to take as a point of departure existing schemes for assessing environmental risks of toxic contaminants. The components of such risk assessments, characterized by the National Academy of Sciences [1] as “hazard identification,” “dose-response assessment,” “exposure assessment,” and “risk characterization”, derive from a systematic examination of the physical, chemical, and toxicological phenomena underlying the risk: the emission rate of the toxicant, its dispersion in air and water, the chemical transformations occurring during transport, and the relationship between the dose to the exposed organism (usually man) and the toxicological effect.

Keywords

Risk Assessment Quantitative Risk Assessment Hazard Identification Risk Assessment Scheme Base Risk Assessment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • Lawrence W. Barnthouse
    • 1
  • Gary S. Sayler
    • 2
  • Glenn W. SuterII
    • 3
  1. 1.Environmental Sciences DivisionOak Ridge National LaboratoryOak RidgeUSA
  2. 2.Graduate Program in EcologyThe University of TennesseeKnoxvilleUSA
  3. 3.Environmental Sciences DivisionOak Ridge National LaboratoryOak RidgeUSA

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