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Cell to Cell Signals in Plant, Animal and Microbial Symbiosis pp 237–254Cite as

Peptide and Carbohydrate Moieties as Molecular Signals in Animal Cell Recognition

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Part of the book series: NATO ASI Series ((ASIH,volume 17))

Abstract

Cell to cell and to substratum interactions are usually mediated by specific ligands and receptors. During the last decade, various cell surface receptors were evidenced, they include carbohydrate binding and peptide binding proteins. Cell surface carbohydrate specific receptors may be lectins (Goldstein et al, 1980), ectoglycosyltransferases or glycosidases. Glycolipids, glycoproteins and proteoglycans have been shown to interact with lectins on the surface of a large number of animal cells as well as parasites, bacteria and viruses (for reviews, see Monsigny et al, 1979, 1983, 1984 a, Monsigny 1984, Ashwell and Harford 1982, Liener et al, 1986, Lis and Sharon 1986, Mirelman, 1986, Sharon, 1984). Conversely, a given cell expresses on its surface a set of specific glycoconjugates which may be involved in recognition mechanisms. These glycoconjugates include glycolipids, glycoproteins and glycosaminoglycans (see Schrével et al., 1981 for a review on the cytochemistry of cell surface glycoconjugates). Their biosynthesis involves a number of different glycosyltransferases, glycosidases and/or epimerases and sulfotransferases. The nature and the number of the glycoconjugates are modulated depending on the type, on the maturation or on the transformation state of cells.

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Authors and Affiliations

  1. Laboratoire de Biochimie Cellulaire et Moléculaire des Glycoconjugués Centre de Biophysique Moléculaire, C.N.R.S. et Université d’Orléans, 1, Rue Haute, 45071, Orleans Cedex 2, France

    M. Monsigny, A. C. Roche, C. Kieda, R. Mayer & P. Midoux

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  1. M. Monsigny
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  2. A. C. Roche
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  3. C. Kieda
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  4. R. Mayer
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  5. P. Midoux
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Editors and Affiliations

  1. Dipartimento di Biologia Vegetale, Università di Torino, Viale Mattioli 25, 10125, Torino, Italy

    Silvano Scannerini  & Paola Bonfante-Fasolo  & 

  2. Old College, University of Edinburgh, South Bridge, EH8 9YL, Edinbourgh, UK

    David Smith

  3. Station de Genetique et d’Amelioration des Plantes de Dijon, INRA, B.V 1540, 21034, Dijon, France

    Vivienne Gianinazzi-Pearson

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© 1988 Springer-Verlag Berlin Heidelberg

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Monsigny, M., Roche, A.C., Kieda, C., Mayer, R., Midoux, P. (1988). Peptide and Carbohydrate Moieties as Molecular Signals in Animal Cell Recognition. In: Scannerini, S., Smith, D., Bonfante-Fasolo, P., Gianinazzi-Pearson, V. (eds) Cell to Cell Signals in Plant, Animal and Microbial Symbiosis. NATO ASI Series, vol 17. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73154-9_17

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  • DOI: https://doi.org/10.1007/978-3-642-73154-9_17

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