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Glia-Promoting Factors and the Control of Oligodendroglial Growth During Brain Development and Regeneration

  • Dana Giulian
  • Joseph F. Krebs
Conference paper
Part of the NATO ASI Series book series (volume 22)

Abstract

The central nervous system (CNS) relies upon complex interactions among glial cells to regulate metabolic functions and to direct structural organization of neural networks. The contributions that astroglia, oligodendroglia, and microglia make to brain function are incompletely understood and include the support of tissue structure, production of myelin membrane, or mediation of inflammatory responses. One way to explore these cellular functions is to determine when and how glia are activated.

Keywords

Retinal Ganglion Cell Myelin Membrane C1300 Cell Line Retinal Ganglion Cell Axon Retinal Ganglion Cell Layer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Benveniste EN, Merrill JE (1986) Stimulation of oligodendroglial proliferation and maturation by Interleukin-2. Nature 321:610–613PubMedCrossRefGoogle Scholar
  2. Giulian D (1980) Isolation of ganglion cells from the retina. Brain Res 189:135–155PubMedCrossRefGoogle Scholar
  3. Giulian D (1984) Peptides from the regenerating central nervous system of goldfish stimulate glia. Proc Nat Acad Sci 81:3567–3571PubMedCrossRefGoogle Scholar
  4. Giulian D, Iwanij V, Stuckenbrok H (1985) The response of optic tract glia during regeneration of the goldfish visual system I. Biosynthetic activity within different glial population after transection of retinal ganglion cell axons. Brain Res 339:87–96PubMedCrossRefGoogle Scholar
  5. Giulian D, Iwanij V (1985) The response of optic tract glia during regeneration of the goldfish visual system II. Tectal factors stimulate optic tract glia. Brain Res 339:97–104PubMedCrossRefGoogle Scholar
  6. Giulian D, Lachman LB (1985) Interleukin-1 stimulates astroglial proliferation after brain injury. Science 228:497–499PubMedCrossRefGoogle Scholar
  7. Giulian D, Baker TJ (1985) Peptides released by ameboid microglia regulate astroglial proliferation. J Cell Biol 101:2411–2415PubMedCrossRefGoogle Scholar
  8. Giulian D, Tomozawa Y, Hindman H, Allen R (1985) Peptides from the regenerating central nervous system promote specific populations of macroglia. Proc Natl Acad Sci USA 82:4287–4290PubMedCrossRefGoogle Scholar
  9. Giulian D, Baker TJ (1986) Characterization of ameboid microglia isolated from the developing mammalian brain. J Neuroscience 6:2163Google Scholar
  10. Giulian D, Allen RL, Baker TJ, Tomozawa Y (1986a) Brain peptides and glial growth. 1) G1ial-promoting factors as regulators of gliogenesis in the developing and injured central nervous system J Cell Biology 102:803–811CrossRefGoogle Scholar
  11. Giulian D, Young D (1986) Brain peptides and glial growth. 2) Identification of cells that secrete glial promoting factors. J Cell Biol 102:812–817PubMedCrossRefGoogle Scholar
  12. Giulian D, Baker TJ, Shih LN, Lachman LB (1986b) Interleukin-1 of the central nervous system is produced by ameboid microglia. J Exp Med 164:594–604PubMedCrossRefGoogle Scholar
  13. Giulian D (1987) Ameboid microglia as effectors of inflammation in the central nervous system. J Neurosci Res, in pressGoogle Scholar
  14. McMorris FA, Smith TM, DeSalvo S, Furlanetto RW (1986) IGF-I/Somatomedin-C: A potent inducer of oligodendrocyte development. Proc Natl Acad Sci USA 83:822–826PubMedCrossRefGoogle Scholar
  15. Raff MC, Fields KL, Hakomori S, Mirsky R, Pruss RM, Winter J (1979) Cell type specific markers for distinguishing and studying neurons and the major classes of glial cells in culture. Brain Res 174:283–308PubMedCrossRefGoogle Scholar
  16. Rio-Hortega P del (1932) Microglia. In: Cytology and Cellular Pathology of the Nervous System, (ed., W Penfield), Paul P Hocker, Inc., New York, Vol. 2, pp. 481–584Google Scholar
  17. Saneto RP, Altman A, Knobler RL, Johnson HM, de Vellis J (1986) Interleukin-2 inhibition of oligodendrocyte progenitor cell proliferation depends on expression of the TAC receptor. Proc Nat Acad Sci 83:9221–9225PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • Dana Giulian
    • 1
  • Joseph F. Krebs
    • 2
  1. 1.Department of NeurologyBaylor College of MedicineHoustonUSA
  2. 2.Program of NeuroscienceBaylor College of MedicineHoustonUSA

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