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Behavioural and Immunological Changes in the Aging Rat

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Neural Development and Regeneration

Part of the book series: NATO ASI Series ((ASIH,volume 22))

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Abstract

Main features of the aging process in the rat are marked changes in immunological activities and in behavioural performances.

Both of them can be attributed to a progressive loss of integration within the brain and between the brain on one hand and the neuroendocrine and immunological systems on the other.

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References

  • Williams D I (1971) Maze exploration in the rat under different levels of illumination. Anim Behav 19: 365–367

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  • Angelucci L, Ghirardi O, Patacchioli FR, Ramacci MT (1986) Disinhibition of the hypothalamo - pituitary - adrenocortical axis as a marker of brain aging in the rat: a model for the study of anti-aging agents. Clin Neurophanracol 9: 104–106

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  • Fabris N, Piantanelli L (1981) In: Adelman R, Roth J (eds) Hormones and aging. CRC Press, Palm Beach

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Author information

Authors and Affiliations

  1. Sigma Tau Biological Research Laboratories, 00040, Pomezia, Italy

    P. Foresta, O. Ghirardi, C. Albertoni & M. T. Ramacci

  2. Dept. of Pharmacology II, La Sapienza University of Rome, Italy

    L. Angelucci

Authors
  1. P. Foresta
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  2. O. Ghirardi
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  3. C. Albertoni
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  4. M. T. Ramacci
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  5. L. Angelucci
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Editor information

Editors and Affiliations

  1. Istituto di Scienze Farmacologiche, Facoltà di Farmacia, Università di Milano, Via Balzaretti 9, 20129, Milano, Italy

    A. Gorio

  2. Department of Human Biological Chemistry and Genetics, Marine Biomedical Institute, University of Texas Medical Branch, Galveston, TX, 77550, USA

    J. R. Perez-Polo

  3. Mental Retardation Research Center #68-177, Department of Anatomy and Department of Psychiatry and Biobehavioral Science, University of California, LA, 760 Westwood Plaza, Los Angeles, CA, 90024, USA

    J. de Vellis

  4. Department of Human Biological, Chemistry and Genetics and Department of Neurology, Marine Biomedical Institute, University of Texas Medical Branch, 200 University Blvd., #519, Galveston, TX, 77550, USA

    B. Haber

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© 1988 Springer-Verlag Berlin Heidelberg

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Foresta, P., Ghirardi, O., Albertoni, C., Ramacci, M.T., Angelucci, L. (1988). Behavioural and Immunological Changes in the Aging Rat. In: Gorio, A., Perez-Polo, J.R., de Vellis, J., Haber, B. (eds) Neural Development and Regeneration. NATO ASI Series, vol 22. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73148-8_59

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  • DOI: https://doi.org/10.1007/978-3-642-73148-8_59

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-73150-1

  • Online ISBN: 978-3-642-73148-8

  • eBook Packages: Springer Book Archive

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