Effect of EGF on the Labeling of Various RNA Species and of Proteins from Subcellular Fractions in Primary Rat Astroglial Cell Cultures

  • R. Avola
  • D. F. Condorelli
  • L. Turpeenoja
  • M. Renis
  • N. Ragusa
  • F. Ingrao
  • S. Reale
  • A. M. G. Stella
Conference paper
Part of the NATO ASI Series book series (volume 22)

Abstract

The ability of epidermal growth factor (EGF) to stimulate cell growth, proliferation and differentiation has been shown for a variety of cell types. Rat cerebral astrocytes bind high amounts of EGF and are responsive to the mitogenic stimulation of EGF when cultured in serum-free medium (1).

Keywords

Cellulose Phenol 

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References

  1. 1).
    Simpson DC, Morrison R, de Vellis J, Herschman HR (1982) Epidermal growth factor binding and mitogen activity on purified populations of cells from central nervous system. J Neurosci Res 8:453–462PubMedCrossRefGoogle Scholar
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    Avola R, Condorelli DF, Surrentino S, Turpeenoja L, Costa A, Giuffrida Stella AM (1987) Effect of epidermal growth factor and insulin on DNA and RNA labeling in primary rat astroglial cell cultures. J Neurosci Res (submitted).Google Scholar
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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • R. Avola
    • 1
  • D. F. Condorelli
    • 1
  • L. Turpeenoja
    • 1
  • M. Renis
    • 1
  • N. Ragusa
    • 1
  • F. Ingrao
    • 1
  • S. Reale
    • 1
  • A. M. G. Stella
    • 1
  1. 1.Institute of Biochemistry, Faculty of MedicineUniversity of CataniaCataniaItaly

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