Effect of EGF on the Labeling of Various RNA Species and of Proteins from Subcellular Fractions in Primary Rat Astroglial Cell Cultures
The ability of epidermal growth factor (EGF) to stimulate cell growth, proliferation and differentiation has been shown for a variety of cell types. Rat cerebral astrocytes bind high amounts of EGF and are responsive to the mitogenic stimulation of EGF when cultured in serum-free medium (1).
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- 2).Avola R, Condorelli DF, Surrentino S, Turpeenoja L, Costa A, Giuffrida Stella AM (1987) Effect of epidermal growth factor and insulin on DNA and RNA labeling in primary rat astroglial cell cultures. J Neurosci Res (submitted).Google Scholar
- 5).Serra I, Avola R, Condorelli DF, Surrentino S, Renis M, Kamiyama M, Hashim GA, Giuffrida AM (1986) Acetylation and phosphorylation of histones and non-histone chromosomal proteins in neuronal and glial nuclei purified from cerebral hemispheres of developing rat brain. J Neurochem 46:1881–1887PubMedCrossRefGoogle Scholar