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Rate Limiting Events in Neurite Outgrowth

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Neural Development and Regeneration

Part of the book series: NATO ASI Series ((ASIH,volume 22))

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Abstract

Neurite outgrowth is one of the early cellular events leading to the differentiation of the neuronal cell. The timing and rate of neurite outgrowth is of crucial importance since the first synaptical contact established appears to have certain advantages in the process of selection during the maturation of the nervous system (Changeux and Danchin, 1976). The rate of neurite outgrowth determines the success or failure in the regeneration phenomena. Indeed, neurons of the central nervous system have the ability to regenerate neurites if provided a proper environment (Benfey and Aguayo, 1982). Therefore the identification of the biochemical events which increase the rate of neurite outgrowth could as well increase our chances to influence the regeneration of functional connections.

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Author information

Authors and Affiliations

  1. Friedrich Miescher Institut, P.O. Box 2543, CH-4002, Basel, Switzerland

    D. Monard

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  1. D. Monard
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Editor information

Editors and Affiliations

  1. Istituto di Scienze Farmacologiche, Facoltà di Farmacia, Università di Milano, Via Balzaretti 9, 20129, Milano, Italy

    A. Gorio

  2. Department of Human Biological Chemistry and Genetics, Marine Biomedical Institute, University of Texas Medical Branch, Galveston, TX, 77550, USA

    J. R. Perez-Polo

  3. Mental Retardation Research Center #68-177, Department of Anatomy and Department of Psychiatry and Biobehavioral Science, University of California, LA, 760 Westwood Plaza, Los Angeles, CA, 90024, USA

    J. de Vellis

  4. Department of Human Biological, Chemistry and Genetics and Department of Neurology, Marine Biomedical Institute, University of Texas Medical Branch, 200 University Blvd., #519, Galveston, TX, 77550, USA

    B. Haber

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© 1988 Springer-Verlag Berlin Heidelberg

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Monard, D. (1988). Rate Limiting Events in Neurite Outgrowth. In: Gorio, A., Perez-Polo, J.R., de Vellis, J., Haber, B. (eds) Neural Development and Regeneration. NATO ASI Series, vol 22. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73148-8_11

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  • DOI: https://doi.org/10.1007/978-3-642-73148-8_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-73150-1

  • Online ISBN: 978-3-642-73148-8

  • eBook Packages: Springer Book Archive

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