Comparison of the Effects of Sodium N-Benzyl-D-glucamine Dithiocarbamate and Ditripentat on the Toxicity, Excretion, and Tissue Distribution of Cadmium in Mice
The administration of sodium N-benzyl-D-glucamine dithiocarbamate (N-BG-DC) to rats pretreated with cadmium can effectively remove cadmium from the body (Kojima et al. 1986 a, b). The purpose of the present study was to examine the comparative influence of this chelator and that of CaDTPA (calcium — complex of diethylenetriamine pentaacetic acid) on the excretion of cadmium in mice exposed to this metal. In previous experiments CaDTPA appeared to be one of the most effective antidotes in cadmium intoxication (Eybl et al. 1984).
KeywordsTissue Distribution Repeated Administration Tissue Content Diethylenetriamine Pentaacetic Acid Cadmium Toxicity
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