Paramecium pp 141-154 | Cite as

Organization and Expression of the Nuclear Genome

  • Manfred Freiburg


During the last decade enormous progress was made in the investigation of the structure of the ciliate genome. Whereas for a long time ciliates have been thought to be rather burlesque relicts of evolution of interest only as an ecological niche for a few enthusiasts, they are now becoming more and more important for the research on basic mechanisms of the molecular biology of eukaryotic genes. Most of this progress was made on a few genera of ciliates: among the hypotrichs Oxytricha, Stylonychia and Euplotes and among the holotrichs essentially on Tetrahymena (see Gall 1984). Paramecium, most important in the past, seems to be somewhat ousted from the centre of interest in this field of research. Nevertheless, as it was demonstrated very recently by the discovery of its deviation in the usage of the “universal” genetic code, Paramecium and its molecular genetics remain most important for our understanding of the organization and evolution of eukaryotic genes.


Genome Reorganization Paramecium Bursaria Macronuclear Development Hypotrichous Ciliate Macronuclear Anlagen 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • Manfred Freiburg
    • 1
  1. 1.Zoologisches Institut der Westfälischen Wilhelms-Universität MünsterMünsterGermany

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