Doesn’t metoclopramide allow a significant decrease in antacid consumption?

  • G. Cargill
Conference paper


Metoclopramide, by its action on the inferior esophageal sphincter, and on the motility of the lower esophagus, decreases the incidence of gastroesophageal reflux. It is therefore logical to think that this substance may permit reduction in the intake of antacids.


Placebo Cimetidine Metoclopramide 


  1. 1.
    McCallum RW et al. (1977) A controlled trial of Metoclopramide in symptomatic gastroesophageal reflux. New Engl J Med 296, 7:354–357PubMedCrossRefGoogle Scholar
  2. 2.
    Bright-Asare P, El Bassoussi M (1980) Cimetidine, Metoclopramide or placebo in the treatment of symptomatic gastroesophageal reflux. J Clin Gastroenterology, 149–156Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • G. Cargill
    • 1
  1. 1.ParisFrance

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