The increase of intra-parietal esophageal collagen could provide elements in the evaluation of motor disorders associated with esophagitis
A factor of prime importance in the development of reflux-esophagitis is the prolonged presence of damaging gastric contents in the esophageal lumen. Gastroesophageal reflux as such is a physiological event, the refluate is removed from the esophagus passively by gravity in the upright patient, and actively by secondary peristalsis or, most frequently, after swallowing. During sleep the only available clearing mode is secondary peristalsis.
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