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Rosmarinic Acid: Production in Plant Cell Cultures

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Book cover Medicinal and Aromatic Plants I

Part of the book series: Biotechnology in Agriculture and Forestry ((AGRICULTURE,volume 4))

Abstract

Rosmarinic acid, or α-0-caffeoyl-3,4-dihydroxyphenyllactic acid (Fig. 1), is a representative of a major class of plant secondary metabolites, the ester- or amide-linked conjugates of hydroxycinnamic acids. These compounds, along with the flavonoid tannins, are believed to serve as the substrates for peroxidases and polyphenol oxidases during the browning of damaged plant tissues and the hypersensitive response to pathogen attack (Tomiyama et al. 1967). Auto-oxidation and enzymic oxidation convert the hydroxycinnamoyl moiety to various reactive species which can readily couple covalently with electron-deficient centers in proteins, nucleic acids and other metabolites (Pierpoint et al. 1977; Igarashi and Yasui 1985). Since this process can rapidly destroy the functional integrity of a cell, hydroxycinnamoyl conjugates in living cells must normally be sequestered in a cellular compartment which isolates them from oxidative enzyme catalysis. The limited evidence on this point indicates that the soluble conjugates are normally stored within the central vacuole (Chaprin and Ellis 1984). There is also a pool of insoluble conjugates associated with the cell wall (El-Basyouni et al. 1964), but their metabolic relationship to the soluble conjugates remains unknown.

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Author information

Authors and Affiliations

  1. Department of Chemistry and Biochemistry, University of Guelph, Guelph, Ontario, N1G 2W1, Canada

    W. De-Eknamkul

  2. Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Chulalong Kom University, Bangkok, 10500, Thailand

    B. E. Ellis

Authors
  1. W. De-Eknamkul
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  2. B. E. Ellis
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Editors and Affiliations

  1. A-137, New Friends Colony, New Delhi, 110065, India

    Y. P. S. Bajaj

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© 1988 Springer-Verlag Berlin Heidelberg

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De-Eknamkul, W., Ellis, B.E. (1988). Rosmarinic Acid: Production in Plant Cell Cultures. In: Bajaj, Y.P.S. (eds) Medicinal and Aromatic Plants I. Biotechnology in Agriculture and Forestry, vol 4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73026-9_17

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  • DOI: https://doi.org/10.1007/978-3-642-73026-9_17

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-73028-3

  • Online ISBN: 978-3-642-73026-9

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