Healing of Pure Epidermal Wounds in Man: A Quantitative Study
Epidermal wound healing (EWH) is a complex process involving two properties of epidermal cells, migration and proliferation. The kinetics of this process are largely unknown. This has led us to propose a new system which permits the quantification of EWH. Epidermis is composed of keratinocytes and “nonkeratinocytes”, including Langerhans’ cells, Merkel’s cells, and melanocytes. Using our model both qualitative and quantitative studies can be performed to establish the behavior of these cells during epidermal regeneration. In this work, attention will focus on keratinocytes and melanocytes.
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