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Neuroendokrinologie und Schlaf

  • Chapter
Schlaf-Wach-Funktionen

Zusammenfassung

Der Schlaf ist nicht nur durch eine erhebliche physiologische Aktivität gekennzeichnet, sondern auch durch charakteristische Sekretionsmuster von Kortisol und Wachstumshormon. Die Kortisolsekretion weist während der ersten Hälfte der Nacht niedrige Werte auf und nimmt in der zweiten Hälfte nach einem ersten Anstieg zwischen 2.00 h und 3.00 h zu, um gegen Morgen die Höchstwerte des 24-h-Zyklus zu erreichen. Umgekehrt ist die Phase der schlafassoziierten Höchstsekretion von Wachstumshormon zeitlich eng an den Schlafbeginn gebunden. Da sowohl die Schlafarchitektur, wie auch die endokrine Aktivität bei Patienten mit affektiven Erkrankungen charakteristisch verändert sind, haben Untersuchungen zur Schlafendokrinologie in den letzten Jahren besonderes Interesse gefunden (Steiger et al. 1987 b). Neben der Sekretion von Kortisol und Wachstumshormon weisen auch Untersuchungen zur Sekretion von Prolaktin, Testosteron und Thyreotropin auf die Existenz schlafbezogener Charakteristika hin.

Diese Arbeit wurde aus Mitteln der Deutschen Forschungsgemeinschaft (Ho 940/1-2) unterstützt.

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Authors
  1. A. Steiger
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  2. F. Holsboer
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Editors and Affiliations

  1. Psychiatrischen Klinik und Poliklinik, Univresität München, Nußbaumstraße 7, D-8000, München 2, Deutschland

    Hanns Hippius (Direktor) & Max Schmauss (Oberarzt) (Direktor) &  (Oberarzt)

  2. Psychiatrischen Klinik, Universität Göttingen, v.-Siebold-Straße 5, D-3400, Göttingen, Deutschland

    Eckart Rüther (Direktor) (Direktor)

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© 1988 Springer-Verlag Berlin Heidelberg

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Steiger, A., Holsboer, F. (1988). Neuroendokrinologie und Schlaf. In: Hippius, H., Rüther, E., Schmauss, M. (eds) Schlaf-Wach-Funktionen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72923-2_15

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  • DOI: https://doi.org/10.1007/978-3-642-72923-2_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-18230-6

  • Online ISBN: 978-3-642-72923-2

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