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Studies on the Plasmodium Falciparum 195,000 Molecular Mass Merozoite Surface Antigen Precursor

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Part of the book series: NATO ASI Series ((ASIH,volume 11))

Abstract

One of the proteins synthesized by the asexual blood stage of malaria which has been studied in some detail is the precursor to the major merozoite surface antigens (PMMSA), a glycoprotein that is synthesized throughout schizogony and present on the merozoite surface in processed form (Holder & Freeman, 1982, 1984; Howard et al., 1985). Complete or partial nucleotide sequences of the gene for this protein from a number of Plasmodium falciparum strains have been reported (Holder, et al., 1985; Mackay et al., 1985; Cheung et al., 1985; Weber et al,1986). Some features of the protein and its gene will be discussed here, in particular studies we have performed with a West African (Wellcome) strain of the parasite.

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© 1987 Springer-Verlag Berlin Heidelberg

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Holder, A.A., Hillman, Y., Nicholls, S.C., Davey, L.S. (1987). Studies on the Plasmodium Falciparum 195,000 Molecular Mass Merozoite Surface Antigen Precursor. In: Chang, KP., Snary, D. (eds) Host-Parasite Cellular and Molecular Interactions in Protozoal Infections. NATO ASI Series, vol 11. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72840-2_31

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  • DOI: https://doi.org/10.1007/978-3-642-72840-2_31

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-72842-6

  • Online ISBN: 978-3-642-72840-2

  • eBook Packages: Springer Book Archive

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