The Structure, Localization, and Function of the Lipophosphoglycan of Leishmania Donovani
The protozoan parasite Leishmania donovani is able to successfully live in two harsh hydrolytic environments in its digenetic life cycle: as an extracellular promastigote in the alimentary tract of its sandfly vector and as an intracellular amastigote in lysosomes of macrophages of its mammalian host. That L. donovani has adapted to survive in such hostile environments is most likely due to protection conferred by specialized molecules on the parasite’s cell surface.
KeywordsTrypanosoma Brucei Variable Surface Glycoprotein Mild Acid Hydrolysis Leishmania DONOVANI Intracellular Amastigote
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