Infectivity of Leishmania Promastigotes is Dependent on the Expression of a 65,000 Dalton Surface Antigen
Leishmania spp., a digenetic trypanosomatid protozoan, is an obligate intracellular parasite of mononuclear phagocytes transmitted by phlebotomine sandflies. The parasite cycles between a flagellated motile promastigote stage in the insect vector and a non-motile intracellular amastigote stage parasitizing the mammalian phagocytic cells. Differentiation into amastigote occurs after surface attachment and entry of promastigotes into mononuclear phagocytes.
KeywordsCarbohydrate Electrophoresis Capron Peri Myeloma
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