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Infectivity of Leishmania Promastigotes is Dependent on the Expression of a 65,000 Dalton Surface Antigen

  • F. Santoro
  • M. Kweider
  • J. L. Lemesre
  • F. Darcy
  • F. S. Rizvi
Part of the NATO ASI Series book series (volume 11)

Abstract

Leishmania spp., a digenetic trypanosomatid protozoan, is an obligate intracellular parasite of mononuclear phagocytes transmitted by phlebotomine sandflies. The parasite cycles between a flagellated motile promastigote stage in the insect vector and a non-motile intracellular amastigote stage parasitizing the mammalian phagocytic cells. Differentiation into amastigote occurs after surface attachment and entry of promastigotes into mononuclear phagocytes.

Keywords

Mononuclear Phagocyte Infective Stage Surface Antigenic Expression Obligate Intracellular Parasite Phase Parasite 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • F. Santoro
    • 1
  • M. Kweider
    • 1
  • J. L. Lemesre
    • 1
  • F. Darcy
    • 1
  • F. S. Rizvi
    • 1
  1. 1.Centre d’Immunologie et de Biologie ParasitaireUnité Mixte INSERM 167 CNRS 624, Institut PasteurLille CédexFrance

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