Minimal Invasive Cancer of the Cervix: Morphologic Definitions and Clinical Consequences

  • E. Holzer


The concept of ‘microcarcinoma’ was introduced into cervical pathology by Mestwerdt in 1947. It was defined on the basis of depth of invasion and limited with regard to growth to a maximum depth of 5 mm (Mestwerdt 1953).


Tumor Volume Intraepithelial Neoplasia Vessel Involvement Cervical Pathology Conization Specimen 
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© Springer-Verlag Berlin Heidelberg 1988

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  • E. Holzer

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