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Serotonin and Mood: Neuroendocrine Aspects

  • Conference paper
Neuroendocrinology of Mood

Part of the book series: Current Topics in Neuroendocrinology ((CT NEUROENDOCRI,volume 8))

Abstract

The role of serotonin (5-HT) in the pathophysiology of mood disorders has been intensively investigated during the past 25 years (Meltzer and Lowy 1987). If 5- HT is involved in the etiology of affective disorders and the mechanism of action of thymoleptic drugs, it must have a significant role, direct or indirect, in the regulation of somatic processes that are disturbed in these mood disorders. In fact, 5-HT has been shown to have an important influence on mood itself, as well as on sleep, sexual activity, appetite, circadian rhythms, neuroendocrine function, anxiety, motor activity, and cognitive function, all of which are disturbed in affective disorders (Meltzer and Lowy 1987).

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  1. Department of Psychiatry, School of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA

    H. Y. Meltzer & J. F. Nash Jr.

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  1. H. Y. Meltzer
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  1. Pharmakologisches Institut, Universität Heidelberg, 1m Neuenheimer Feld 366, 6900, Heidelberg, Germany

    Detlev Ganten M.D., Ph.D.

  2. Rockefeller University, York Avenue, and 66th Street, New York, NY, 10021, USA

    Donald Pfaff Ph.D.

  3. Karolinska Institute, P.O. Box 60400, 10401, Stockholm, Sweden

    Kjell Fuxe M.D.

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Meltzer, H.Y., Nash, J.F. (1988). Serotonin and Mood: Neuroendocrine Aspects. In: Ganten, D., Pfaff, D., Fuxe, K. (eds) Neuroendocrinology of Mood. Current Topics in Neuroendocrinology, vol 8. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72738-2_7

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