Immune Interactions with Islet Cells: Implications for the Pathogenesis of Insulin-Dependent Diabetes Mellitus

  • J. Nerup
  • T. Mandrup-PouIsen
  • J. Mølvig
  • G. Spinas


Occasionally a single scientific paper may signal a new era in the study of a disease. The 1965 paper by Willy Gepts was such a signal [1]. The (re)discovery of insulitis provided the impetus for new thoughts about the pathogenesis of insulin-dependent diabetes mellitus (IDDM) and for the emergence of a new research field: immunology of IDDM.


Islet Cell Islet Cell Antibody IDDM Patient Islet Allograft Immune Interaction 
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© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • J. Nerup
  • T. Mandrup-PouIsen
  • J. Mølvig
  • G. Spinas

There are no affiliations available

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