Mononitrate II pp 178-183 | Cite as

Cardiovascular Function and Exercise Tolerance of Patients with Myocardial Infarction and Standardized Physical Training after Isosorbide-5-Mononitrate and Nifedipine

  • R. Rost
  • B. Bjarnason
  • K. de Meirleir
Part of the International Boehringer Mannheim Symposia book series (BOEHRINGER)


The present study was performed in order to obtain information about the effects of two of the most important drugs in antianginal treatment on exercise tolerance and cardiovascular response during physical stress. This question is of major significance since a great number of cardiac patients are now exercising for therapeutic reasons. Most of them are under the effects of a wide variety of drugs which may influence their working capacity as well as the physiological reactions which are used to determine exercise intensity, such as heart rate, lactic acid concentration, exercise perception, etc. Whereas there has been a lot of research on the effects of beta-receptor blockers (BB), which predominantly influence exercise reactions, knowledge of the effects of calcium antagonists or nitrates has up to now been limited.


Exercise Tolerance Lactic Acid Concentration Coronary Patient Repeated Medication Acute Trial 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • R. Rost
  • B. Bjarnason
  • K. de Meirleir

There are no affiliations available

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