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Expression von OKM5 Antigen an humanen Keratinozyten in vitro nach Stimulation mit Gamma-Interferon

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Dermatologie und Rheuma
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Zusammenfassung

Humane epidermale Zellen (EZ) sind potente Stimulatoren der antigenspezifischen allogenen T-Lymphozyten-Aktivierung. Diese funktionelle Eigenschaft beruht auf die Anwesenheit von Klasse II-Alloantigen tragenden Langerhans-Zellen [8]. Es gibt zwischenzeitlich zahlreiche Hinweise, daß bei vielen Dermatosen Keratinozyten ebenfalls HLA-DR-Antigen exprimieren können [4]. Es wurde außerdem mitgeteilt, daß Interferon-γ (IFN-γ) in der Lage ist, HLA-DR-Synthese und Expression bei gezüchteten normalen humanen Keratinozyten zu bewirken [9].

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© 1987 Springer-Verlag Berlin Heidelberg

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Simon, M., Hunyadi, J. (1987). Expression von OKM5 Antigen an humanen Keratinozyten in vitro nach Stimulation mit Gamma-Interferon. In: Holzmann, H., Altmeyer, P., Marsch, W.C., Vogel, H.G. (eds) Dermatologie und Rheuma. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72668-2_58

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  • DOI: https://doi.org/10.1007/978-3-642-72668-2_58

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-72669-9

  • Online ISBN: 978-3-642-72668-2

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