Abstract
Tumours of germ cell origin are very rare. In the Manchester Children’s Registry from 1954–1978 141 cases were recorded. There appears, however, to be a continuing trend to increasing incidence, first noticed in 1973, so that the annual incidence is now four per million person years, compared with one in 1954. The factors responsible for this increase have not been clearly defined. Malformations, particularly of the central nervous and genito-urinary systems, may be found in association with benign teratomas or yolk sac tumours [1].
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Birch JM, Marsden HB, Swindell R (1982) Pre-natal factors in the origin of germ cell tumours of childhood. Carcinogenesis 3(1):75–80
Cameron KM (1981) The pathology of testicular tumours. In: Peckham MJ (ed) The management of testicular tumours. Arnold, London, pp 20–21
Tucker DF, Oliver RT, Travers P, et al (1985) Serum marker potential of placental alkaline phosphatase-like activity in testicular germ cell tumours evaluated by H17E2 monoclonal antibody assay. Br J Cancer 51(5):631–639
Cangir A, Smith J, van Eys J (1978) Improved prognosis in children with ovarian cancers following modified VAC (vincristine sulfate, dactinomycin and cyclophosphamide) chemotherapy. Cancer 42(3):1234–1238
Einhorn LH, Donohue JP (1977) Cis-diamminedichloroplatinum, vinblastine and bleomycin combination chemotherapy in disseminated testicular cancer. Ann Intern Med 87:293–298
Julian CG, Barrett JM, Richardson RL, et al (1980) Bleomycin, vinblastine and cis-platinum in the treatment of advanced endodermal sinus tumor. Obstet Gynecol 56(3):396–401
Green DM, Brecher ML, Grossi M, et al (1983) The use of different induction and maintenance chemotherapy regimens for the treatment of advanced yolk sac tumors. J Clin Oncol 1(2):111–115
Daugaard G, Rørth M, Hansen HH (1983) Therapy of extragonadal germ-cell tumors. Eur J Cancer Clin Oncol 19(7):895–899
Davis TE, Loprinzi CL, Buchler DA (1984) Combination chemotherapy with cisplatin, vinblastine and bleomycin for endodermal sinus tumor of the ovary. Gynecol Oncol 19:46–52
Flamant F, Schwartz L, Delons E, et al (1984) Nonseminomatous malignant germ cell tumors in children. Multidrug therapy in stages III and IV. Cancer 54:1687–1691
Peckham MJ (1985) The management of testicular cancer. Cancer Topics 5(6):66–68
Bloom HJG (1983) Primary intracranial germ cell tumours. In: Clinics in oncology, vol 2. Saunders, Philadelphia, pp 233–257
Carroll WL, Kempson RL, Govan DE, et al (1985) Conservative management of testicular endodermal sinus tumor in childhood. J Urol 133(6):1011–1014
Rogers P, Pritchard J, Pincott JR, et al (1981) Sacrococcygeal teratoma (ST): review and management of 34 infants. Proc Annu Meet Am Soc Clin Oncol 22:407 [Abstract C-293]
Ein SH, Adeyeimi SD, Mancer K (1980) Benign sacrococcygeal teratomas in infants and children. A 25 year review. Ann Surg 191:382–384
Gross RE, Clatworthy BTW Jr, Meeker IA (1951) Sacrococcygeal teratomas in infants and children. A report of 40 cases. Surg Gynecol Obstet 92:341–354
Green DM (1983) The diagnosis and treatment of yolk sac tumors in infants and children. Cancer Treat Rev 10:265–288
Tait D, Peckham MJ, Hendry WF, Goldstraw P (1984) Post-chemotherapy surgery in advanced non-seminomatous germ-cell testicular tumours: The significance of histology with particular reference to differentiated (mature) teratoma. Br J Cancer 50:601–609
Dehner LP (1983) Gonadal and extragonadal germ cell neoplasia of childhood. Hum Pathol 14(6):493–511
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1989 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Barrett, A. (1989). The Place of Surgery in the Management of Germ Cell Tumours in Childhood. In: Spitz, L., Wurnig, P., Angerpointner, T.A. (eds) Pediatric Surgical Oncology. Progress in Pediatric Surgery, vol 22. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72643-9_7
Download citation
DOI: https://doi.org/10.1007/978-3-642-72643-9_7
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-72645-3
Online ISBN: 978-3-642-72643-9
eBook Packages: Springer Book Archive