Treatment of Liver Cirrhosis

  • J. T. Galambos
  • W. D. Warren
  • W. J. MillikanJr.
  • J. M. Henderson
  • D. Simon
  • W. S. Brooks
  • S. P. Riepe
Conference paper


Morphologically, cirrhosis can be defined as an entity. However, the physiologic and clinical abnormalities produced by cirrhosis are heterogeneous. Cirrhosis cannot be used as a homogeneous entity in clinical studies without clear-cut definition of the type of patients involved and the manifestation of the severity of their disease. Neither the clinical illness nor death of cirrhotic patients is necessarily related to liver disease. For example, 40% of 4455 deaths in cirrhosis were due to causes other than hepatic or renal failure, GI bleeding, or infection. One of the best examples of the heterogeneity of the clinical manifestation of cirrhosis is provided by the data published recently by various investigators purporting to identify the key determinants which predict the prognosis for cirrhotic patients. Although the various investigators used similar statistical methods, what appeared to be prognostic in one institution was not in another, and vice versa [1–5].


Central Venous Pressure Esophageal Varix Ascitic Fluid Variceal Bleeding Gastric Varix 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Heidelberg 1987

Authors and Affiliations

  • J. T. Galambos
    • 1
  • W. D. Warren
    • 1
  • W. J. MillikanJr.
    • 1
  • J. M. Henderson
    • 1
  • D. Simon
    • 1
  • W. S. Brooks
    • 1
  • S. P. Riepe
    • 1
  1. 1.Departments of Medicine and SurgeryEmory University School of MedicineAtlantaUSA

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