Neutralization and Receptor Recognition of Human T-Lymphotropic Retroviruses

  • R. A. Weiss
  • P. R. Clapham
  • A. G. Dalgleish
  • J. N. Weber
Conference paper
Part of the Haematology and Blood Transfusion / Hämatologie und Bluttransfusion book series (HAEMATOLOGY, volume 31)


Like other enveloped viruses, the outer membrane antigens of retroviruses present target antigens for neutralizing antibodies, and also play a key role in interacting with cell-surface receptors for initial stages of infection. We have investigated these attributes of the envelopes of human T-lymphotropic retroviruses (Weiss 1985; Wong-Staal and Gallo 1985) and our studies are briefly summarized here.


Cellular Tropism Neutralization Antigen Outer Membrane Antigen Detect Neutralize Activity 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • R. A. Weiss
    • 1
  • P. R. Clapham
    • 1
  • A. G. Dalgleish
    • 1
  • J. N. Weber
    • 1
  1. 1.Chester Beatty LaboratoriesInstitute of Cancer ResearchLondonEngland

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