Cancer Clonality and Field Theory
A field theory  models malignancy as a state “added” to, and capable of interacting with, other normal states composing the field associated with any living cell. The theory may be downscaled from the (multi) cellular to the level of topologically disordered motions of chromatin and DNA strings occurring before or at interphase when chromatids are iteratively dilated in cells mitotically driven by a potential from special “source” cells. Clonal development of tumors might result from the extremely low efficiency with which the driving potential activates its corresponding gene(s) P in one (or exceedingly few) source-dependent cell. Most normal cells are assumed to have gene P “curled up” in some nonexpressed configuration in a segment j (say) within a lattice or plaquette unfolded from crumpled preimages during chromatid decondensation [11–13].
KeywordsCage Leukemia Resid Sponge Nite
Unable to display preview. Download preview PDF.
- 2.De-Gennes P (1979) Scaling concepts in polymer physics. Cornell University Press, IthacaGoogle Scholar
- 3.Suzuki M (1983) Brownian motion with geometrical restrictions. In: Yonezawa F, Ninomiya T (eds) Topological disorder in condensed matter. Springer, Berlin Heidelberg New York Tokyo (Springer series in solid-state sciences, vol 46)Google Scholar
- 5.Mandelbrot BB (1983) The fractal geometry of nature. Freeman, San FranciscoGoogle Scholar
- 6.Abraham RH (1985) Dynamics, vol 0–4. Sci Front PressGoogle Scholar
- 7.Percival I, Richards D (1985) Introduction to dynamics. Cambridge University Press, CambridgeGoogle Scholar
- 8.Krylov NS (1979) Raboty po obosnovaniiu statisticheskoi fiziki. Princeton University Press, PrincetonGoogle Scholar
- 9.Lichtenberg AJ, Lieberman MA (1982) Regular and stochastic motion. Springer, Berlin Heidelberg New YorkGoogle Scholar
- 10.Zaslavsky GM (1985) Chaos in dynamic systems. Harwood, LondonGoogle Scholar