Skip to main content

Computed Tomography Evaluation of the Upper Abdomen in β-Thalassemia

  • Chapter
Book cover Radiology of Thalassemia
  • 107 Accesses

Abstract

Clinical management of β-thalassemia depends on repeated blood transfusions and on chelation therapy. Computed tomography (CT) can provide the opportunity to relate CT density to iron deposition; therefore, CT appearance may be essential for evaluation of abdominal organs for the degree of hemochromatosis.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Long JA, Doppman JL, Nienhuis AW and Mills SR (1980) Computed tomographic analysis of beta-thalassemic syndromes with hemochromatosis: pathologic findings with clinical and laboratory correlations. J Comput Assist Tomogr 4: 159–165

    Article  PubMed  Google Scholar 

  2. Mill SR, Doppman JL, Nienhuis AW (1977) Computed tomography in the diagnosis of excessive iron storage of the liver, J Comput Assist Tomogr 1: 101–104

    Article  Google Scholar 

  3. Houang MTW, Arozena X, Skalicka A, Huehns ER (1979) Correlation between computed tomo-graphic values and liver iron content in thalassemia major with iron overload. Lancet 1: 1322–1323

    Article  PubMed  CAS  Google Scholar 

  4. Magid D, Fishman EK, Siegelman SS (1984) Computed tomography of the spleen and liver in sickle cell disease. A J R 143: 245–249

    CAS  Google Scholar 

  5. Mitnick JS, Bosniak MA, Megibow AJ, Karpatkin M, Feiner HD, Kutin N, VanNatta F, Piomelli S (1981) CT in beta-thalassemia: iron depo-sition in the liver, spleen and lymph nodes. A J R 136: 1191–1194

    CAS  Google Scholar 

  6. Nienhuis AW, Peterson DT, Henry W (1977) Evaluation of endocrine and cardiac function in patients with iron overload on chelation therapy. In: Zaino EC (ed) Chelation therapy in chronic iron overload. Symposia Specialists

    Google Scholar 

  7. Champan RWG, Williams G, Bydder G, Dick R, Sherlock S, Kreel L (1980) Computed tomography for determining liver iron content in primary hemochromatosis. Br Med J 28: 440

    Google Scholar 

  8. Howard JM, Ghent CN, Carey LS, Flanagan PR, Valberg LS (1983) Diagnostic efficacy of hepatic computed tomography in the detection of body iron overload. Gastroenterology 84: 209

    PubMed  CAS  Google Scholar 

  9. Goldberg HI, Cann CE, Moss AA, Ohto M, Brito A, Federle M (1982) Noninvasive quantification of liver iron in dogs with hemochromatosis using dual-energy CT scanning. Invest Radiol 17: 375–380

    Article  PubMed  CAS  Google Scholar 

  10. Brasch RC, Wesbey GE, Gooding CA, Koerper MA (1984) Magnetic resonance imaging of transfusional hemosiderosis complicating thalassemia major. Radiology 150: 767–771

    PubMed  CAS  Google Scholar 

  11. Erttman R, Hausdorf G and Landbeck G (1983) Pancreatic sonography in thalassemia major. Clin Pediatr (Philadelphia) 195: 97–99

    Google Scholar 

  12. Grossman H, Dische R, Winchester P, Canale V (1971) Renal enlargement in thalassemia major. Radiology 100: 645–648

    PubMed  CAS  Google Scholar 

  13. Winchester PH, Cerwin R, Dische K, Canale V (1973) Hemosiderin laden lymph nodes. A J R 118: 222–226

    CAS  Google Scholar 

  14. Parsons C (1977) Abdominal lymphography in thalassemia major. Clin Radiol 18: 545–548

    Article  Google Scholar 

  15. Gollan JL (1983) Diagnosis of hemochromatosis. Gastroenterology 84: 418–421

    PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1989 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Gouliamos, A.D. (1989). Computed Tomography Evaluation of the Upper Abdomen in β-Thalassemia. In: Papavasiliou, C., Cambouris, T., Fessas, P. (eds) Radiology of Thalassemia. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72587-6_8

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-72587-6_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-72589-0

  • Online ISBN: 978-3-642-72587-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics