Thalassemia: Pathophysiology, Clinical and Laboratory Findings

  • A. Fertakis


Thalassemias are a heterogeneous group of disorders of hemoglobin (Hb) synthesis, which have in common a reduced rate of synthesis of one or more of the globin chains of normal human Hb [25]. This leads to a variable degree of premature cell destruction, ineffective erythropoiesis and/or hemolysis, and, finally, a variable degree of anemia.


Thalassemia Major Beta Thalassemia Globin Chain Thalassemia Intermedium Ineffective Erythropoiesis 
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© Springer-Verlag Berlin Heidelberg 1989

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  • A. Fertakis

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