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Ultrasound-Guided Procedures for Prenatal Diagnosis of Hemoglobinopathies

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Radiology of Thalassemia

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Abstract

Prenatal diagnosis of various congenital abnormalities and inherited diseases, with selective termination of affected pregnancies, has been universally accepted and extensively applied for the last 15 years [1, 2]. In particular, prenatal diagnosis of hemoglobinopathies including thalassemia is generally performed by globin chain synthesis studies on fetal blood samples obtained by fetoscopic or ultrasound-guided techniques in the second trimester of pregnancy [3, 4], or by DNA analysis of chorionic villi samples obtained by ultrasound-guided techniques in the first trimester of pregnancy [5, 6]. Ultrasound scanning plays a central role in enhancing the safety and effectiveness of these diagnostic procedures.

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Authors
  1. A. Antsaklis
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Editors and Affiliations

  1. Department of Radiology, University of Athens, School of Medicine, Areteion Hospital, 115 28, Athens, Greece

    Constantin Papavasiliou  & Theophanis Cambouris  & 

  2. Department of Internal Medicine, University of Athens, School of Medicine, 115 28, Athens, Greece

    Phaedon Fessas

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© 1989 Springer-Verlag Berlin Heidelberg

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Antsaklis, A. (1989). Ultrasound-Guided Procedures for Prenatal Diagnosis of Hemoglobinopathies. In: Papavasiliou, C., Cambouris, T., Fessas, P. (eds) Radiology of Thalassemia. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72587-6_17

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  • DOI: https://doi.org/10.1007/978-3-642-72587-6_17

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-72589-0

  • Online ISBN: 978-3-642-72587-6

  • eBook Packages: Springer Book Archive

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