Abstract
A novel bacterial toxicity bioassay, the Toxichromotest, has recently been proposed (Reinhartz et al., in press). It is based on the ability of toxic materials to inhibit the de novo synthesis of an inducible enzyme, β-galactosidase, in a mutant strain of Escherichia coli (E. coli) after lyophilic stress.
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References
Reinhartz A, Lampert I, Herzberg M, Fish F (1987) A new, short-term, sensitive bacterial assay kit for the detection of toxicants. Toxicity Assessment 2(2):in press for may 1987
Woods PB, Robinson ML (1981) An investigation of the comparative liposolubilities of beta-adreno-ceptor blocking agents. J Pharm Pharmacol 33:172–173
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© 1987 Springer-Verlag
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Lympany, P., Cassidy, S.L., Henry, J.A. (1987). An Evaluation of the Toxichromotest, a Bacterial Toxicity Bioassay, and an Assessment of its Potential Use in Human Poisoning. In: Chambers, C.M., Chambers, P.L., Davies, D.S. (eds) Mechanisms and Models in Toxicology. Archives of Toxicology, Supplement, vol 11. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72558-6_65
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DOI: https://doi.org/10.1007/978-3-642-72558-6_65
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-17614-5
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