An Evaluation of the Toxichromotest, a Bacterial Toxicity Bioassay, and an Assessment of its Potential Use in Human Poisoning
A novel bacterial toxicity bioassay, the Toxichromotest, has recently been proposed (Reinhartz et al., in press). It is based on the ability of toxic materials to inhibit the de novo synthesis of an inducible enzyme, β-galactosidase, in a mutant strain of Escherichia coli (E. coli) after lyophilic stress.
KeywordsPartition Coefficient Yellow Substrate Timolol Maleate Mercury Chloride Metoprolol Tartrate
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- Reinhartz A, Lampert I, Herzberg M, Fish F (1987) A new, short-term, sensitive bacterial assay kit for the detection of toxicants. Toxicity Assessment 2(2):in press for may 1987Google Scholar