The Effect of Ethanol on the Growth of Rat Embryos: The Role of Stage Dependency and Hyperosmolality
Clinical studies and experimental research have established the teratological relationship between constant ethanol consumption throughout pregnancy, and the occurrence of alcohol embryopathy (AE) in the offspring of alcoholics (as reviewed by Abel, 1982). The implication of social or “binge” drinking is of specific interest because confusion exists concerning advice given to pregnant women about their drinking habits.
KeywordsGlycerol Ethyl Toxicology
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- Beck F, Huxham IM, Gulamhusein AP (1984) Growth of rat embryos in the serum of alcohol drinkers. In: Porter et al. (eds) Mechanisms of alcohol damage in utero. Pitman, London, pp 218–233 (CIBA Foundation Symposium 105)Google Scholar
- Kronick JB (1976) Teratogenic effects of ethyl alcohol administered to pregnant mice. Am J Obstet Gynecol 124:678–680Google Scholar
- Popov VB, Vaisman BL, Puchkov VF, Ignat’eva TV (1982) Toxic action of ethanol and its biotransformation products on post-implantation rat embryos in culture. Bull Eksp Biol Med 72:1707–1710Google Scholar
- Webster WS, Walsh DA, Lipson AH, McEwen SE (1980) Teratogenesis after acute alcohol exposure in inbred and outbred mice. Neurobehav Toxicol 2:227–234Google Scholar