Genital System pp 239-251 | Cite as

Anatomy, Histology, and Ultrastructure (Correlation with Function), Prostate, Rat

  • Chung Lee
  • James M. Holland
Part of the Monographs on Pathology of Laboratory Animals book series (LABORATORY)


The rat prostate is a highly specialized gland. Its sole function is the secretion of prostatic fluid, which constitutes an important component of seminal plasma (Mann and Lutwak-Mann 1981). However, one of the most fascinating characteristics of this organ is its constant dependence upon androgenic hormones for its functional and structural integrity (Lee 1981). The rapid rate of prostatic involution following androgen withdrawal, as by bilateral orchiectomy, and the subsequent equally rapid rate of reactivation of tissue growth upon androgen replacement are predictable and highly reproducible biological phenomena. Therefore, it is not surprising that the rat prostate has become a useful experimental model for scientists in a large variety of biological disciplines.


Seminal Vesicle Lateral Lobe Ventral Prostate Ventral Lobe Lobe Line 
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© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • Chung Lee
  • James M. Holland

There are no affiliations available

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