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Genital System pp 127–134Cite as

Yolk Sac Carcinoma, Rat

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Part of the book series: Monographs on Pathology of Laboratory Animals ((LABORATORY))

Abstract

A yolk sac carcinoma is a pearly white tumor, often with red or brown small foci which are less compact than surrounding firm tumoral tissue. The tumor infiltrates the organ in which it develops, depending upon the method of induction (Fig. 147). Multiple metastases are found mostly in the peritoneum, ovaries, and lymph nodes but also occasionally in lungs, liver, spleen, kidneys, and thymus. Nearly all animals develop the ascitic form of the yolk sac carcinoma.

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References

  • Bullock FD, Curtis MR (1930) Spontaneous tumors of the rat. J Cancer Res 14:1–115

    Google Scholar 

  • Damjanov I (1980) Parietovisceral yolk sac carcinoma in the rat. Am J Pathol 98: 569–572

    PubMed  CAS  Google Scholar 

  • Damjanov I, Sell S (1977) Yolk sac carcinoma grown from rat egg cylinders. JNCI 58:1523–1525

    PubMed  CAS  Google Scholar 

  • Damjanov I, Skreb N, Sell S (1977) Origin of embryo-de-rived yolk sac carcinomas. Int J Cancer 19: 526–530

    Article  PubMed  CAS  Google Scholar 

  • Delacourt MC, Sobis H, Vandeputte M (1976) Immuno- fluorescent localization of alphafetoprotein in yolk-sac carcinomas in the rat. JNCI 57:1375–1377

    PubMed  CAS  Google Scholar 

  • Hooghe R, Zeicher M, Sobis H, Vandeputte M (1974) Yolk-sac carcinomas induced by murine sarcoma vims and producing alphafetoprotein. In: Masseyeff R (ed) Proceedings of the international Conference on Alpha- Feto-Protein. INSERM, Paris, pp 271–273

    Google Scholar 

  • Kobayashi H, Kikuchi K, Maki T, Nishiya I (1965) Two transplantable uterine adenocarcinomas in the rat. JNCI 34:13–20

    PubMed  CAS  Google Scholar 

  • Pierce GB Jr, Midgley AR Jr, Ram JS, Feldman JD (1962) Parietal yolk sac carcinoma: clue to the histogenesis of Reichert’s membrane of the mouse embryo. Am J Pathol 41:549–566

    PubMed  Google Scholar 

  • Sakashita S, Tsukada Y, Nakamura K, Tsuji I, Hirai H (1977) Experimental yolk-sac tumors produced by fetectomy without vims infection in rats. Int J Cancer 20: 83–86

    Article  PubMed  CAS  Google Scholar 

  • Sobis H, Vandeputte M (1973) In utero tumor induction by murine sarcoma vims (Moloney) in the rat. II. Histological and ultrastmctural characteristics. Int J Cancer 11: 543–554

    Article  PubMed  CAS  Google Scholar 

  • Sobis H, Vandeputte M (1977) Yolk sac derived teratomas and carcinomas in hamsters. Eur J Cancer 13: 1175–1181

    Article  PubMed  CAS  Google Scholar 

  • Sobis H, Vandeputte M (1983) Yolk sac-derived malignant tumors develop in the absence of germ cells. Oncodev Biol Med 4:415–422

    PubMed  CAS  Google Scholar 

  • Sobis H, van Hove L, Vandeputte M (1982) Trophoblastic and mesenchymal stmctures in rat yolk sac carcinoma. Int J Cancer 29:181–186

    Article  PubMed  CAS  Google Scholar 

  • Sobis H, van Hove L, Vandeputte M (1983) Yolk-sac carcinoma of extraembryonic origin in the 129 Sv/Sl mouse. Int J Cancer 32:367–371

    Article  PubMed  CAS  Google Scholar 

  • Solter D, Damjanov I (1973) Explanation of extraembryonic parts of 7-day-old mouse egg cylinders. Experientia 29:701–702

    Article  PubMed  CAS  Google Scholar 

  • Stevens LC (1958) Studies on transplantable testicular teratomas of strain 129 mice. JNCI 20:1257–1275

    PubMed  CAS  Google Scholar 

  • Stevens LC (1970) The development of transplantable ter- atocarcinomas from intratesticular grafts of pre- and postimplantation mouse embryos. Dev Biol 21: 364–382

    Article  PubMed  CAS  Google Scholar 

  • Stewart HL, Sass B, Deringer MK, Dunn TB, Liotta LA, Togo S (1984) Pure yolk sac carcinoma of the mouse utems: report of 8 cases. JNCI 73:115–122

    PubMed  CAS  Google Scholar 

  • Symeonidis A, Mori-Chavez P (1952) A transplantable ovarian papillary adenocarcinoma of the rat with ascites implants in the ovary. JNCI 13:409–429

    PubMed  CAS  Google Scholar 

  • Teilum G (1959) Endodermal sinus tumors of the ovary and testis. Comparative morphogenesis of the so-called mesonephroma ovarii (Schiller) and extraembryonic (yolk sac-allantoic) stmctures of the rat’s placenta. Cancer 12:1092–1105

    Article  PubMed  CAS  Google Scholar 

  • Vandeputte M, Sobis H (1978) Experimental tumors derived from extra-embryonal fetal tissue. In: Severi L (ed) Tumours of early life in man and animals, Pemgia Quadrennial Intemational Conferences on Cancer, Perugia, Italy, pp 723–733

    Google Scholar 

  • Vandeputte M, Sobis H, Billiau A, van de Maele B, Leyten R (1973) In utero tumor induction by murine sarcoma vims (Moloney) in the rat. I. Biological characteristics. Int J Cancer 11: 536–542

    Article  PubMed  CAS  Google Scholar 

  • Van Hove L, Sobis H, Vandeputte M (1982) Viral- versus non viral-induced yolk sac tumors in the rat. Oncodev Biol Med 3:97–109

    PubMed  Google Scholar 

  • Van Hove L, Sobis H, Lu YL, Vandeputte M (1984) A rat yolk-sac antigen defined by monoclonal antibodies. Int J Cancer 33: 851–858

    Article  PubMed  Google Scholar 

  • Van Hove L, Sobis H, Lu YL, Vandeputte M (1985) Rat yolk-sac antigen-2 defined by monoclonal antibodies. Int J Cancer 35: 237–244

    Article  PubMed  Google Scholar 

  • Wewer U (1982) Characterization of a rat yolk sac carcinoma cell line. Dev Biol 93: 416–421

    Article  PubMed  CAS  Google Scholar 

  • Wewer U, Albrechtsen R, Ruoslahti E (1981) Laminin, a non-collagenous component of epithelial basement membranes synthesized by a rat yolk sac tumor. Cancer Res 41:1518–1524

    PubMed  CAS  Google Scholar 

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Authors
  1. Halina Sobis
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Editors and Affiliations

  1. New England Regional Primate Research Center, Harvard Medical School, One Pine Hill Drive, 01772, Southborough, MA, USA

    Thomas Carlyle Jones D.V.M., D.Sc. (Professor of Comparative Pathology, Emeritus) & Ronald Duncan Hunt D.V.M. (Professor of Comparative Pathology) (Professor of Comparative Pathology, Emeritus) &  (Professor of Comparative Pathology)

  2. Institut für Experimentelle Pathologie, Medizinische Hochschule Hannover, Konstanty-Gutschow-Strasse 8, 3000, Hannover 61, Federal Republic of Germany

    Ulrich Mohr M.D. (Professor of Experimental Pathology) (Professor of Experimental Pathology)

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© 1987 Springer-Verlag Berlin Heidelberg

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Sobis, H. (1987). Yolk Sac Carcinoma, Rat. In: Jones, T.C., Mohr, U., Hunt, R.D. (eds) Genital System. Monographs on Pathology of Laboratory Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72550-0_19

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  • DOI: https://doi.org/10.1007/978-3-642-72550-0_19

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-72552-4

  • Online ISBN: 978-3-642-72550-0

  • eBook Packages: Springer Book Archive

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