Zusammenfassung
Der Mikrozirkulation als Bindeglied zwischen dem Makrokreislaufsystem und den zu versorgenden Organen, Geweben und Zellen kommt beim Schockgeschehen eine Schlüsselrolle zu. Im Bereich der Gefäße mit weniger als 300 μm Durchmesser ist auf der arteriellen Seite die wesentliche Komponente der Regulation des peripheren Widerstandes lokalisiert, der für die Aufrechterhaltung bzw. Wiederherstellung eines ausreichenden Blutdrucks erforderlich ist. Mit ihrer kapillären und venolären Austauschfläche stellt die Mikrozirkulation andererseits das entscheidende Transportorgan zwischen Blut und Gewebe dar. Darüber hinaus kommt der venolären Mikrozirkulation ein erheblicher Anteil am Volumenreservoir zu.
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Literatur
Bagge, U.: White Blood Cell Rheology. Experimental Studies On The Rheologic L Properties Of White Blood Cells In Man And Rabbit And In The In Vitro Flow System. Göteborg: Thesis 1975
Chien, S.: Blood Rheology And Its Relation To Flow ResiStance And Transcapillary Exchange, With Special Reference To Shock. Advanc. Microcirc., Vol. 2, P. 89. Basel: Karger 1969
Chien, S.: Biophysical Behavior Of Red Cells In Suspensions. In: The Red Blood Cell (Ed. D. M. N. Surgenor), Bd. Ii, P. 1031. New York: Academic Press 1975
Dahlberg, B.: Transcapillary Solute Exchange In Skeletal Muscle After Injury And During Shock. Acta Physiol. Scand. 472, Suppl. (1979)
Dahlen, S.-E., Björk, J., Hedqvist, P., Arfors, K.-E., Hammars Tröm, S., Lindgren, J.-A., Samuelsson, B.: Leukotrienes Promote Plasma, Leakage And Leukocyte Adhesion In Postcapillary Venules: In Vivo Effects With Relevance To The Acute InFlammatory Response. Proc. Nat. Acad. Sei. (Wash.) W, 388 7 (1981)
Del Maestro, R. F., Björk, J., Arfors, K.-E.: Increase In Microvascular Permeability Induced By Enzymatically GeneRated Free Radicals. I. In Vivo Study. Microvasc. Res. 22, 239 (1981)
Driessen, G. K.: Über Den Einfluß Veränderter FließeigenSchaften Des Blutes Auf Die Perfusion Der Mikrozirkulation. Habilitationsschrift, Aachen 1982
Engelson, E. T., Skalak, T. C., Schmid-Schönbein, G. W.: The Microvasculature In Skeletal Muscle: I. Arteriolar NetWork In Rat Spinotrapezius Muscle. Microvasc. Res. 3_0, 29 (1985)
Engler, R. L., Schmid-Schönbein, G. W., Pavelec, R. S.: Leukocyte Capillary Plugging In Myocardial Ischemia And Reperfusion Of The Dog. Amer. J. Path. 111, 98 (1983)
Evans, E. A.: Structural Model for Passive Granulocyte Behaviour Based Qn Mechanical Deformation and Recovery After Deformation Tests. In: White Cell Mechanics: Basic Science and Clinical Aspects (Eds. Meiselman, Lichtman, Lacelle ), P. 53. New York: Liss 1984
F and Hraeus, R.: Die Strömungsverhältnisse Und Die Verteilung Der Blutzellen Im Gefäßsystem. Klin. Wschr. 7, 100 (1928)
Fähraeus, R., Linpqvist, T.: The Viscosity Of Blood In NarRow Capillary Tubes. Amer. J. Physiol. 95, 562 (1931)
Gaehtgens, P.: Flow Of Blood Through Narrow Capillaries: Rheological Mechanisms Determining Capillary Hematocrit And Apparent Viscosity. Biorheology V7, 183 (1980)
Gaehtgens, P.: Deformation and Activation of Leukocytes - Two Contradictory Phenomena? In: White Cell Mechanics: Basic Science and Clinical Aspects (Eds. Meiselman, Lichtman, Lacelle ), P. 159. New York: Liss 1984
Gaehtgens, P., Ley, K., Pries, A. R., Müller, R.: Mutual In Teraction Between Leukocytes And Microvascular Blood Flow. Progr. Appl. Microcirc., Vol. 7, P. 15. Basel: Karger 1985
Gaehtgens, P., Pries, A. R., Nobis, U.: Flow Behaviour Of White Ceils In Capillaries. In: White Cell Mechanics: BaSic Science and Clinical Aspects (Eds. Meiselman, Lichtman, Lacelle ), P. 147. New York: Liss 1984
Gustafsson, L., Appelgren, L., Myrvold, H. E.: Effects Of Increased Plasma Viscosity And Red Blood Cell Aggregation On Blood Viscosity In Vivo. Amer. J. Physiol. 241, H 513 (1981)
Hutchins, P. M., Goldstone, J., Wells, R.: Effects of Hemor Rhagic Shock On The Microvasculature Of Skeletal Muscle. Microvasc. Res. 5, 131 (1973)
Johnson, P. C., Wayland, H.: Regulation of Blood Flow In Single Capillaries. Amer. J. Physiol. 212, 1405 (1967)
Krogh, A.: Studies on The Physiology Of Capillaries. Ii. The Reactions To Local Stimuli Of The Blood Vessels In The Skin And Web Of The Frog. J. Physiol. 55, 412 (1921)
Ley, K., Arfors, K.-E.: Changes In Macromolecular PermeabiLity By Intravascular Generation Of Oxygen-Derived Free RaDicals. Microvasc. Res. 225 (1982)
Ley, K., Pries, A. R., Gaehtgens, P.: Topological Structure Of Rat Mesenteric Microvessel Networks. Microvasc. Res. (Im Druck)
Lindbom, L., Tuma, R. F., Arfors, K.-E.: Influence of Oxygen On Perfused Capillary Density And Capillary Red Cell Velocity In Rabbit Skeletal Mußcle. Microvasc. Res. 19, 197 (1980)
Messmer, K.: Radioactive Microspheres For Regional Blood Flow Measurements: Actual State And Perspectives. Bibl. Anat. (Basel) T8, 194 (1979)
Nobis, U., Pries, A. R., Cokelet, G. R., Gaehtgens, P.: Radial Distribution Of White Cells During Blood Flow In Small Tubes. Microvasc. Res. 29_, 295 (1985)
Pries, A. R., Ley, K., Gaehtgens, P.: Generalization of The F and Hraeus Principle For The Analysis Of Hematocrit Reduction In Microvessel Networks. Amer. J. Physiol. (Zur Publikation Eingereicht T985)
Reinke, W., Johnson, P., Gaehtgens, P.: Effect of Shear Rate Variation on Apparent Viscosity Of Human Blood In Tubes Of 29 To 94 Jam Diameter. Circulat. Res. (Zur Publika-Tion Eingereicht 1985)
Solomon, L. A., Hinshaw/ L. B.: Effect Of Endotoxin On Iso- Gravimetric Capillary Pressure In The Forelimb. Amer. J. Physiol, 214/ 443 (1968)
Schmid-Schönbein, G. W., Skalak, R., Usami, S., Chien, S.S Cell Distribution In Capillary Networks. Microvasc. Res. 19, 18 (1980)
Skalak, R., Chien, S., Schmip-Schönbein, G. W.: Viscoelastic Deformation of White Cells: Theory And Analysis. In: White Cell Mechanics: Basic Science and Clinical Aspects (Eds. Meiselman, Lichtman, Lacelle)/ P. 3. New York: Liss 1984
Taylor, A. E., Granger, D. N.: Exchange of Macromolecules Across The Microcirculation. In: Handbook of Physiology (Ed. Amer. Physiol. Soc.), Section 2, Bd. Iv, P. 467 (1984)
Thülesius, O., Johnson/ P. C.: Pre- and Postcapillary Resistance In Skeletal Muscle. Amer. J. Physiol. 210, 869 (1966)
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Ley, K., Gaehtgens, P. (1987). Mikrozirkulationsstörungen im Schock. In: Kilian, J., Meßmer, K., Ahnefeld, F.W. (eds) Schock. Klinische Anästhesiologie und Intensivtherapie, vol 33. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72533-3_2
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DOI: https://doi.org/10.1007/978-3-642-72533-3_2
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