Factors affecting the viability of cryopreserved allograft heart valves
Allograft heart valves have been used for more than 25 years as replacements for diseased aortic valves and repair of congenital abnormalities. In many instances, particularly paediatric surgery, it is the valve of choice due to its non-obstructive flow, relative freedom from calcification and thromboembolism without anticoagulation therapy. In order to permit valve size matching for recipients, it is necessary to find methods of storage which will maintain cellular viability. The best method which allows infinite, convenient storage is cryopreservation.
KeywordsAortic Valve Heart Valve Cellular Viability Allograft Valve Cryopreserved Allograft
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