Effect of Coronary Occlusion During Percutaneous Transluminal Angioplasty on Systolic and Diastolic Left Ventricular Function, Coronary Hemodynamics, and Myocardial Energetic Metabolism

  • Patrick W. Serruys
  • F. Piscione
  • W. Wijns
  • J. A. J. Hegge
  • E. Harmsen
  • M. van den Brand
  • P. de Feyter
  • J. W. de Jong
  • P. G. Hugenholtz
Conference paper


Until recently, the measurement in man of left ventricular geometry and hemodynamics and the assessment of alteration in myocardial metabolism early after an abrupt occlusion of a major coronary artery were not feasible. Percutaneous transluminal coronary angioplasty (PTCA), however, now provides a unique opportunity to study the time course of these variables during the transient interruption of coronary flow in the balloon occlusion sequence in patients with single-vessel disease and without angiographically demonstrable collateral circulation [1, 2].


Coronary Occlusion Balloon Inflation Occlusion Pressure Left Ventricular Geometry Wall Displacement 
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Copyright information

© Dr. Dietrich Steinkopff Verlag GmbH & Co. KG, Darmstadt 1986

Authors and Affiliations

  • Patrick W. Serruys
    • 2
  • F. Piscione
    • 1
  • W. Wijns
    • 1
  • J. A. J. Hegge
    • 1
  • E. Harmsen
    • 1
  • M. van den Brand
    • 1
  • P. de Feyter
    • 1
  • J. W. de Jong
    • 1
  • P. G. Hugenholtz
    • 1
  1. 1.Catheterization and Cardiochemical Laboratories, ThoraxcenterErasmus UniversityRotterdamThe Netherlands
  2. 2.Catheterization Laboratory ThoraxcenterRotterdamThe Netherlands

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