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Circadian biology of the urinary excretion of calcium, oxalate, phosphorus and uric acid in renal calculous patients

  • Conference paper
Pathogenese und Klinik der Harnsteine XII

Part of the book series: Fortschritte der Urologie und Nephrologie ((2824,volume 25))

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Abstract

Recurrent stone formation in patients with calcium oxalate lithiasis poses a serious problem to clinicians. Three major hypothesis have been proposed to explain renal stone formation: (i) supersaturation of one or more of the components in renal stones, (ii) matrix crystallization and (iii) absence of inhibitory substances in urine. In idiopathic urolithiasis, while the 24 h urinary excretion of the lithogenic substances may well be within the normal ranges, frequent excretion/concentration peaks during the day may exist when nucleation would occur. Such a circadian rhythmicity of lithogenic substances would enhance the risk of stone formation. In the present study therefore, circadian variation of four lithogenic urinary parameters viz., calcium, oxalate, uric acid and inorganic phosphorous has been investigated in patients with urolithiasis.

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Authors and Affiliations

  1. Departments of Biochemistry and Urology, Chandigarh, India

    S. Vaidyanathan

  2. Postgraduate Institute of Medical Education and Research, Chandigarh, India

    Prof. Dr. R. Nath, S. K. Thind & H. Sidhu

  3. Department of Biochemistry, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India

    Prof. Dr. R. Nath

Authors
  1. Prof. Dr. R. Nath
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  2. S. K. Thind
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  3. S. Vaidyanathan
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  4. H. Sidhu
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Editor information

Editors and Affiliations

  1. Univ.-Klinik, Sigmund-Freud-Straße 25, 5300, Bonn 1, Deutschland

    W. Vahlensieck (Direktor d. Urolog.) (Direktor d. Urolog.)

  2. Urologischen Abteilung, Krankenhaus der Stadt Wien-Lainz, Wolkersbergenstraße 1, A-1130, Wien, Österreich

    G. Gasser (Primarius) (Primarius)

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© 1987 Dr. Dietrich Steinkopff Verlag, GmbH & Co. KG., Darmstadt

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Nath, R., Thind, S.K., Vaidyanathan, S., Sidhu, H. (1987). Circadian biology of the urinary excretion of calcium, oxalate, phosphorus and uric acid in renal calculous patients. In: Vahlensieck, W., Gasser, G. (eds) Pathogenese und Klinik der Harnsteine XII. Fortschritte der Urologie und Nephrologie, vol 25. Steinkopff. https://doi.org/10.1007/978-3-642-72399-5_35

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  • DOI: https://doi.org/10.1007/978-3-642-72399-5_35

  • Publisher Name: Steinkopff

  • Print ISBN: 978-3-7985-0713-5

  • Online ISBN: 978-3-642-72399-5

  • eBook Packages: Springer Book Archive

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