Mild but clinically significant metabolic hyperoxaluria and it’s response to pyridoxine

  • G. P. Kasidas
  • G. A. Rose
  • C. T. Samuell
Conference paper
Part of the Fortschritte der Urologie und Nephrologie book series (2824, volume 23)

Abstract

Urinary oxalate is one of the most important risk factors for calcium oxalate urolithiasis. It has been difficult to measure in the past but a number of new methods have recently been described from various parts of the world. Our own automated method (1) was brought into use in February 1984 but even before that we had been measuring up to 30 urine samples per week for many years. As a result, a number of cases of mild hyperoxaluria, defined as metabolic in origin by the finding of raised urinary glycollate have come to light. The first two cases were previously described (2), two other cases without any other metabolic abnormalities were described more recently (3) and the same paper referred to five more cases who also had renal tubular acidosis (RTA). Since that time more cases have been found and this paper considers a group of 14 cases without RTA as well as a follow-up of one of the original two who happened to have RTA as well.

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References

  1. 1.
    Kasidas GP, Rose GA (1985) Ann Clin Biochem 22: 412–419PubMedGoogle Scholar
  2. 2.
    Harrison AR, Kasidas GP, Rose GA (1981) Br Med J 282: 2097–2098CrossRefGoogle Scholar
  3. 3.
    Kasidas GP, Rose GA (1984) Urinary Stone. In: Ryall R, Brockis JG, Marshall V, Finlayson B (eds) Churchill Livingstone pp 138–147Google Scholar
  4. 4.
    Hallson PC, Rose GA (1974) Clin Chim Acta 55: 29–39PubMedCrossRefGoogle Scholar
  5. 5.
    Kasidas GP, Rose GA (1979) Clin Chim Acta 96: 25–36PubMedCrossRefGoogle Scholar
  6. 6.
    Woodring MJ, Fisher DH, Storvick CA (1964) Clin Chem 10: 479–488PubMedCrossRefGoogle Scholar

Copyright information

© Dr. Dietrich Steinkopff Verlag, GmbH & Co. KG., Darmstadt 1985

Authors and Affiliations

  • G. P. Kasidas
    • 1
  • G. A. Rose
    • 1
    • 2
  • C. T. Samuell
    • 1
  1. 1.St. Peter’s Hospitals and Institute of UrologyLondonUK
  2. 2.St. Paul’s HospitalLondonUK

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