Plasma insulin and C-peptide in classified subgroups of calcium stone formers — influence of a test meal and relationship to urinary calcium and phosphate

  • G. Rümenapf
  • Paul Otto Schwille
Conference paper
Part of the Fortschritte der Urologie und Nephrologie book series (2824, volume 23)

Abstract

Gastrintestinal (GI) and pancreatic hormones may alter the composition of urine and thus influence the risk of stone formation (1–4). Special interest has been focused on insulin, a hormone long known to increase urinary calcium (Ca) excretion (4, 5). In unclassified recurrent calcium urolithiasis (RCU) patients, exaggerated and sustained plasma insulin levels were observed after oral administration of carbohydrate-rich test meals (2, 6) or pure carbohydrate loads (6), giving rise to speculations on a possible role of insulin in stone pathophysiology.

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Copyright information

© Dr. Dietrich Steinkopff Verlag, GmbH & Co. KG., Darmstadt 1980

Authors and Affiliations

  • G. Rümenapf
    • 1
  • Paul Otto Schwille
    • 1
    • 2
  1. 1.Mineral Metabolism and Endocrine Research Laboratory, Departments of Surgery and UrologyUniversity of ErlangenWest Germany
  2. 2.Experimental Surgery and UrologyUniversity HospitalErlangenGermany

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