Pathophysiology of calcium, magnesium and phosphorus and their importance in renal stones
Renal stone formation is widely acknowledged to be associated with certain risk factors. As discussed elsewhere at this meeting these include hypercalcuria, increased oxalate excretion and a decrease in urinary inhibitor. It is to be noted that high magnesium concentrations act as inhibitors of stone formation and magnesium salts are frequently used in the treatment of renal stones. The purpose is to briefly review normal kidney calcium and magnesium transport and phosphorus and to make some suggestions as to their defects in idiopathic hypercalciuria and renal stone formation.
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